Small vessel disease (SVD) is a pathology that affects microcirculation in the brain and can be detected by imaging techniques such as magnetic resonance and computed tomography. SVD leaves a heterogeneous phenotype of imaging markers, ranging from white matter changes to microbleeds. The pathogenesis...
small vessel disease Acronyms Any of multiple small cerebral infarcts in the corona radiata, internal capsule, striatum, thalamus, basis pontis, and/or cerebellum, occasionally preceded by transient symptoms, due to occlusion or stenosis of small penetrating branches of the middle and posterior cerebral...
The main disease symptoms were cognitive impairment, gait disturbances unrelated to post-stroke hemiparesis, and MRI changes including WMH, lacunae, microbleeds and dilated perivascular spaces (Table 2). Table 2 Clinical symptoms and MRI signs in patients with CSVD. Full size table Differences in mea...
Vasculitis is a process caused by inflammation of blood vessel walls and results in disorders of organs because of insufficeint blood supply. Classification on large-, medium-, or small-vessel vasculitis is one of possible ways to classify vasculitis, but there is no precise classification yet.1...
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among elderly individuals and is recognized as a major vascular contributor to dementia, cognitive decline, gait impairment, mood disturbance and stroke. However, clinical symptoms are often highly inconsistent in nature and severity...
Both ISMN and cilostazol have been widely used for ischemic heart disease, peripheral vascular disease, or secondary prevention of atherothromboembolic stroke for years, with known, acceptable safety profiles. Despite concerns that adverse symptoms attributable to these drugs would discourage compliance, ...
This was managed with intravenous methylprednisone followed by oral prednisone and intravenous cyclophosphamide, which led to an improvement in his symptoms and estimated GFR. The man died of a massive pulmonary haemorrhage at home, a few weeks post discharge, after having discontinued his ...
In patients who present with symptoms mimicking appendicitis ultrasound can suggest the diagnosis of unsuspected acute terminal ileitis.58,59The ultrasound findings are similar to those of Crohn's disease, including a thickened echo-poor wall, diminished peristalsis and enlarged mesenteric lymph ...
Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people and is related to vascular risk factors and cognitive and motor impairment, ultimately leading to dementia or parkinsonism in some. In general, the relations are weak, and not all subjects with SVD...
A bidirectional communication exists between the brain and the gut, in which the gut microbiota influences cognitive function and vice-versa. Gut dysbiosis has been linked to several diseases, including Alzheimer's disease and related dementias (ADRD). H