The 5 year survival rates in 18 patients with lymphoma undergoing curative surgery was 48 per cent while in patients whose surgery was considered palliative the figure was 12 per cent ( P < 0路001). In the 29 patients with carcinoma, 17 had curative surgery and 12 a palliative procedure ...
T-cell/histiocyte-rich large B-cell lymphoma: a heterogeneous entity with derivation from germinal center B cells. T-cell/histiocyte-rich large B-cell non-Hodgkin's lymphoma (THRLBCL) is an unusual morphologic variant of diffuse large B-cell lymphoma. We reviewed 30 cas... MS Lim,M Beaty...
Small cell lung cancer (SCLC) remains a deadly form of cancer, with a 5-year survival rate of less than 10 percent, necessitating novel therapies. Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncofetal protein that is emerging as a therapeutic target and is co-expressed wi...
Small cell lung cancer is characterized by early metastases and rapid growth. While initially very responsive to both chemotherapy and radiation therapy, the majority of patients will have recurrent disease or become refractory to treatment. The 5-year survival of patients with small cell lung...
cell lymphoma, diffuse large B-cell lymphoma (DLBCL),10inflammatory myofibroblastic tumor,11and non-small cell lung cancer (NSCLC).12Fusion of echinoderm microtubule-associated protein-like 4 withALK(EML4-ALK) in NSCLC was identified in 2007 by Soda et al.12this rearrangement of theALKgene has...
Non-small cell lung cancer is the most common type of lung cancer, accounting for about 80% of all cases. In 2024, the overall five-year survival rate for patients diagnosed with lung cancer is 25% in the ...
Activity of topotecan 21-day infusion in patients with previously treated large cell lymphoma: long-term follow-up of an Eastern Cooperative Oncology Group... The purpose of this study was to determine the activity of topotecan given by 21-day continuous infusion in patients previously treated wi...
NSCLC: Non-small cell lung cancer EGFR : Epidermal growth factor receptor ALK : Anaplastic lymphoma kinase OS: Overall survival ECOG PS: Eastern Cooperative Oncology Group Performance Status Scale References Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. ...
Multiple myeloma is a post-germinal center B-cell neoplasm, characterized by the proliferation of malignant bone marrow plasma cells, whose survival and proliferation is sustained by growth factors and cytokines present in the bone marrow microenvironment. Among them, IL-6 triggers the signal downstre...
Adams H, Tzankov A, Lugli A, Zlobec I (2009) New time-dependent approach to analyse the prognostic significance of immunohistochemical biomarkers in colon cancer and diffuse large B-cell lymphoma. J Clin Pathol 62: 986–997. Article CAS Google Scholar Albain KS, Crowley JJ, LeBlanc M, ...