为庆祝Cell杂志创刊50周年,2024年11月14日,中国科学院分子细胞科学卓越创新中心的陈玲玲研究员与韩国首尔大学的V. Narry Kim教授受邀在Cell上发表了一篇题为Small and Long Noncoding RNAs: Past, Present, and Future的综述,全面而深入地回顾了small RNA与lncRNA从最初发现至今的历程,详细梳理了它们在作用机制上的...
Emerging knowledge indicates that non-coding RNAs, including microRNAs (miRNAs) and long-noncoding RNAs (lncRNAs), have a pivotal role in bone development and the pathogenesis of bone-related disorders. Most recently, miRNAs have started to be regarded as potential biomarkers or targets for various...
long (long non-coding RNA) and small non-coding RNAs (for example, microRNA) have been demonstrated to be essential for brain development and higher cognitive abilities, and to be involved in psychiatric disease. Long non-coding RNAs, highly expressed in the brain and expanded in mammalian ...
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are the two main types of non-coding RNAs that play crucial roles in plant growth and development. However, their specific roles in the fiber growth of ramie plant (Boehmeria nivea L. Gaud) remain largely unknown. Methods In this study...
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Emerging role of microRNAs and long noncoding RNAs in respiratory disease. Chest. 2014;146(1):193–204. Article CAS PubMed Google Scholar Chen TY, Liu CH, Chen TH, Chen MR, Liu SW, Lin P, et al. Conditioned media of adipose-derived stem cells suppresses sidestream cigarette smoke ...
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Long non-coding RNAs compose an important level of epigenetic regulation in normal physiology and disease. Despite the plethora of publications of lncRNAs in human cancer, the landscape is still unclear.Microarray analysis in 44 NSCLC paired specimens was followed by qPCR-based validation in 29 (...
Pancreatic cancer has the worst prognosis among common tumors which is attributed to its aggressive phenotype, diagnosis at advanced, inoperable stages, and resistance to systemic therapy. Non-coding RNAs (ncRNAs) such as microRNAs, long non-coding RNAs, and circular RNAs have been established as ...
Long Noncoding RNA (lncRNA) Small Nucleolar RNA Host Gene 16 (SNHG16) Predicts Poor Prognosis and Sorafenib Resistance in Hepatocellular Carcinoma. BACKGROUND Long noncoding RNAs (lncRNAs) play important roles in cancer development and therapeutic resistance. However, the role of small nucleolar RN...