SLC7A11-IN-1 是一种 SLC7A11 抑制剂,具有抗增殖活性和抗肿瘤活性,抑制细胞侵袭和转移,诱导细胞凋亡和细胞周期停滞,可用于研究神经系统疾病。 规格价格库存数量 1 mg ¥ 3,450 现货 大包装 & 定制 加入购物车 实验操作小课堂 SLC7A11-IN-1产品问题解答 问化合物带有盐酸盐离子、硫酸盐离子等是否和其...
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SLC7A11-IN-1 | MedChemExpress (MCE) 英文名称: 总访问: 144 国产/进口: 进口 半年访问: 20 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 电询 最后更新: 2024-11-4 货号: HY-149979 CAS 号: 参考报价: 电询 立即询价 电话咨询 ...
SLC7A11-IN-1 中文名: 中文别名: CBNumber: CB514291578 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 SLC7A11-IN-1化学性质 形态: Solid 颜色: White to off-white 安全信息 SLC7A11-IN-1性质、用途与生产工艺 SLC7A11-IN-1上下游产品信息 ...
摘要: Solute carrier family 7, membrane 11 (SLC7A11) or (xCT) is a component of the cysteine-glutamate transporter, which plays a critical role in glutathione homeostasis which is import... 查看全部>>关键词:laryngeal squamous cell carcinoma SLC7A11 Ki-67 p53 biomarker ...
The gene,SLC7A11,which encodes the solute carrier family 7 member 11 (anionic amino acid transporter light chain,xCT),has been reported to be implicated in multiple processes such as in pheomelanin production,cell proliferation and migration,Kaposi's sarcoma herpesvirus (KSHV) entry into the host...
Moreover, there was a downregulation in the expression of SLC7A11 mRNA and protein in IOC cardiomyocytes, suggesting a potential compensatory mechanism to counteract oxidative damage. TEM further elucidated cardiac mitochondrial injuries in IOC rats, including focal vacuolization, swelling, crest ...
Ferroptosis, a regulated form of cell necrosis was previously reported to be induced upon pharmacological targeting of the cystine transporter SLC7A11 in Head and neck Squamous Cell Carcinoma (HNSCC). Whether tumors arising in a context of chronic infection with Human Papillomavirus (HPV) are sensiti...
Ferroptosis, a regulated form of cell necrosis was previously reported to be induced upon pharmacological targeting of the cystine transporter SLC7A11 in Head and neck Squamous Cell Carcinoma (HNSCC). Whether tumors arising in a context of chronic infection with Human Papillomavirus (HPV) are sensiti...
Oncogenic KRAS is a major driver in lung adenocarcinoma (LUAD) that has yet to be therapeutically conquered. Here we report that the SLC7A11/glutathione axis displays metabolic synthetic lethality with oncogenic KRAS. Through metabolomics approaches, we found that mutationally activated KRAS strikingly...