昆明地区中小学学生的 5-HT 转运体蛋白基因(SLC6A4)与儿童品行 障碍的关联性林雁张京晶黄高贵张翼宇芮溧姚树祥Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
ZZL-7 is a fast-acting antidepressant that enhances 5-HT (serotonin) signaling in forebrain circuits. ZZL-7 disrupts the interaction between the 5-HT transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN), reduces extracellular 5-HT concentration and down...
Serotonin (5-HT) transporter (SLC6A4; SERT)Mouse studies suggest that a selective serotonin reuptake inhibitor (SSRI) could help treat cognitive impairment associated with Down syndrome.Nature Publishing Group USScience-Business eXchangedoi:10.1038/scibx.2010.835None...
Serotonin (5-HT) transporter (SLC6A4; SERT)Mouse and human studies suggest selective serotonin reuptake inhibitors (SSRIs) could help prevent AD.Science-Business eXchangedoi:10.1038/scibx.2014.717
Nineteen drug-free depressed psychiatric inpatients (nine suicide attempters) and nine neurological control subjects underwent lumbar puncture and psychiatric evaluation. CSF and plasma concentrations of AVP, serotonin (5-HT), 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), and cortisol ...
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and ...
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which h...
Saliva samples were collected at enrollment and genetic testing was done of cytochrome P450 liver enzyme, 5HTTLPR and 5HT2A variants to guide clinical choice and dosage of psychotropic medications. As such, a significant component of our sample includes treatment refractory, as well as medication ...
p pBackground/p pThe serotonin (5-hydroxytryptamin; 5-HT) system has a central role in the circuitry of cognition and emotions. Multiple lines of evidence suggest that genetic variation in the serotonin transporter gene (itSLC6A4/it; it5-HTT/it) is associated with schizophrenia and ...
本文明确未经治疗的年轻女性厌食症(anorexia nervosa,AN)患者SLC6A4基因甲基化特点及其与mRNA表达,血小板5-HT水平及临床症状严重程度的关系;探索AN患者在临床症状改善后SLC6A4基因甲基化,mRNA表达,血小板5-HT水平的变化及其对临床症状变化的影响.研究得出SLC6A4基因甲基化参与AN的病理机制,且未经治疗AN患者的S LC6A4...