昆明地区中小学学生的 5-HT 转运体蛋白基因(SLC6A4)与儿童品行 障碍的关联性林雁张京晶黄高贵张翼宇芮溧姚树祥Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
ZZL-7 is a fast-acting antidepressant that enhances 5-HT (serotonin) signaling in forebrain circuits. ZZL-7 disrupts the interaction between the 5-HT transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN), reduces extracellular 5-HT concentration and down...
南京医科大学硕士学位论文 反社会人格障碍患者攻击行为与sLC6A4基因、MAoA基因 多态硅的相关挂研究 摘要 羁酌 探讨中国汉族人群SLC6A4基因(5一羟色胺转移蛋白基因、5.HTT)启 动手区基因多态蛀、MAoA《单腔氧化酶A)基因启动子区可变数目串联 重复多态性(MAOA.vNTR)与反社会人格障碍攻击行为遗传易感性的 关系。
Anti-5-HTR2B(5-hydroxytryptamine(serotonin)receptor 2B) 5-羟色胺受体2B(5-HT/seroton yb-1892R Anti-5-HTR2A 5-羟色胺受体2A抗体 yb-1056R Anti-5-HTT/SERT(Serotoninreuptake transporter) 5-羟色胺转运蛋白抗体 yb-1893R Anti-5-HTR3(5-hydroxytryptamine (serotonin) receptor 3a) 5-羟色胺受...
在涉及基因型与药物部分分别增加了CYP2B6,5-羟色胺转运体SLC6A4,5-羟色胺2A受体HTR2A以及5-羟色胺与去甲肾上腺素再摄取抑制剂(SNRIs),类SSRIs活性的5-羟色胺(5-HT)调节剂相关内容,并更新了基于基因多态性的5-HT再摄取抑制剂类药物应用建议.本文对该指南相关内容进行解读,以期为我国5-HT再摄取抑制剂类...
背景与目的:人类编码5-HT转运体(serotonin transporter,5-HTT)的基因SLC6A4多态性中研究较多的是5-HTTLPR和rs25531,根据二者对转录和表达5-HTT的影响可分为高、中、低表达三类基因型,已有研究表明5-HTT不同表达水平基因型与慢性疼痛综合征的严重程度密切相关,在热疼痛阈值及阿片药物的镇痛作用上也证实5-HTT低表达...
Serotonin (5-HT) functions as a neurotransmitter in the central nervous system (CNS) where it is involved in a range of behaviors and psychological processes including mood, appetite, anxiety, social interactions, and hormone release. Studies have reported increased whole blood 5-HT levels in indi...
Serotonergic signalling is initiated by the release of serotonin (5-HT) from the pre-synaptic neuronal cell into the synaptic cleft. Termination of neurotransmitter action, a key step that determines the intensity and duration of signalling, occurs by re-uptake of the extracellular serotonin back ...
Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial. BACKGROUND: Antidepressants exhibit a variety of pharmacological actions including inhibition of the serotonin and noradrenaline transporters. We wished to... - 《Br J Psychiatry》 被引量: 128发表: 2011年...
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) trans... L Pezawas,A Meyer-Lindenberg,A Goldman,... - 《Neuroimage》 被引量: 0发表: 2012年 Oestradiol alters central 5-HT1A receptor binding potential differences related to psychosocial stress but not differences ...