This study focuses on the upregulation of piR-000699 after hypoxia/reoxygenation treatment in aging cardiomyocytes by observing hypoxia/reoxygenation (H/R) injury indicators and ferroptosis-related indicators and clarifying the role of piR-000699 in H/R injury caused by ferroptosis in aging ...
Show abstract Iron Metabolism in Ferroptosis 2020, Frontiers in Cell and Developmental Biology Iron metabolism and iron disorders revisited in the hepcidin era 2020, Haematologica Current understanding of iron homeostasis 2017, American Journal of Clinical Nutrition View all citing articles on Scopus ...
赵云所向披靡,战功显赫,映射出SLC39A14转运金属离子的强大而复杂的生理功能——SLC39A14主要转运锰离子,并对铁、锌等多种金属离子具有选择特性。在铁过载的情况下,SLC39A14转运铁离子并介导铁死亡(ferroptosis)发生;SLC39A14介导的锌离子转运影响多种疾病发生发展。 图5 SLC39A14转运多种金属离子 及调控铁死亡重要功...
Conclusion: Silencing SLC39A14 inhibits ferroptosis and tumor progression, potentially involving the regulation of the cGMP-PKG signaling pathway.doi:10.1186/s12885-023-11637-0Zhang, YunwenWu, XinghaiZhu, JiyongLu, RuibinOuyang, YianBioMed CentralBMC Cancer...
Methods: R language was employed for the differential analysis of the dataset, revealing the correlation between ferroptosis and calcification. The experimental approaches encompassed both in vitro and in vivo studies, incorporating the use of iron chelators and models of iron overload. Additionally, ...