SLC26A4-AS1在泌乳素瘤,生长激素瘤和促肾上腺皮质激素瘤中表达无明显差异.与SLC26A4-AS1高表达组相比,SLC26A4-AS1低表达组中肿瘤体积≥3 cm^(3)的比例明显增加,侵袭性垂体瘤的比例明显增加,差异具有统计学意义(P<0.05).结论 SLC26A4-AS1在侵袭性垂体瘤中表达降低,SLC26A4-AS1的低表达与肿瘤体积和侵袭性...
对过表达SLC26A4-AS1的未分化甲状腺癌CAL-62细胞ERBB4表达的影响.生物信息学分析miR-221-3p与SLC26A4-AS1和ERBB4的潜在结合位点,并通过双荧光素酶报告基因实验验证.CCK-8方法和Transwell实验检测敲减ERBB4对过表达SLC26A4-AS1的未分化甲状腺癌CAL-62细胞增殖,迁移和侵袭的影响.结果 过表达SLC26A4-AS1增加未分化...
Intriguingly, SLC26A4-AS1 could simultaneously interact with DDX5 and the E3 ligase TRIM25, which promoting DDX5 degradation through the ubiquitin-proteasome pathway. In particular, SLC26A4-AS1 inhibited expression of multiple DNA double-strand breaks (DSBs) repair genes, especially genes coding ...
SLC26A4-AS1在泌乳素瘤,生长激素瘤和促肾上腺皮质激素瘤中表达无明显差异.与SLC26A4-AS1高表达组相比,SLC26A4-AS1低表达组中肿瘤体积≥3 cm^(3)的比例明显增加,侵袭性垂体瘤的比例明显增加,差异具有统计学意义(P<0.05).结论 SLC26A4-AS1在侵袭...
Intriguingly, SLC26A4-AS1 could simultaneously interact with DDX5 and the E3 ligase TRIM25, which promoting DDX5 degradation through the ubiquitin-proteasome pathway. In particular, SLC26A4-AS1 inhibited expression of multiple DNA double-strand breaks (DSBs) repair genes, especially genes coding ...
Intriguingly, SLC26A4-AS1 could simultaneously interact with DDX5 and the E3 ligase TRIM25, which promoting DDX5 degradation through the ubiquitin-proteasome pathway. In particular, SLC26A4-AS1 inhibited expression of multiple DNA double-strand breaks (DSBs) repair genes, especially genes coding ...
Results The expression of SLC26A4-AS1 was decreased in invasive pituitary adenomas compared with noninvasive pituitary adenomas. There was no difference of SLC26A4-AS1 expression between PRL adenoma, GH adenoma and ACTH adenoma and nonfunctional adenomas. Compared with...