Imaging of the skeleton using radioactive substances has been possible for over 40 years. Improvements in radiopharmaceuticals and instrumentation have taken place over this time, most notably the introduction of technetium-labeled phosphates in the 1970s and the development of the dual-headed gamma ca...
BackgroundSkeletal scintigraphy remains a valuable tool in the initial and subsequent evaluation of the skeletal system in patients with a diagnosis of primary or metastatic neoplasms.MethodsWe discuss radiopharmaceuticals, nuclear medicine imaging techniques, and current as well as future oncological ...
The present study aims to develop and characterize a controlled-release delivery system for protein therapeutics in skeletal muscle regeneration following an acute injury. The therapeutic protein, a membrane-GPI anchored protein called Cripto, was immobi
Labeled targets obtained from 5 μ g of total RNA were used for hybridization on each microarray. Purified RNA was labe- led with a miRCURYTM LNA miR Array Labeling kit (Exiqon, Vedbak, Denmark). The Hy3TM-labeled samples and Hy5TM-labeled reference pool RNA samples were then mixed...
In a typical study, labeled phenylala- nine is infused intravenously over 8 h. Over the last 3 h, unlabeled amino acids are also infused. This provides addi- tional substrate for muscle protein synthesis; normally, what is seen is a spike in synthetic rate. However, inevitably, mus- cle ...
Data also uncovered a likely age-induced dysregulation of the OXPHOS system in females noticed by, for example, the downregulation of the core subunit NDUFV2 from complex I as well of the subunit 1 (UQCRC1) from complex III, which was accompanied by an upregulation of subunits 7 (LOC...
Studies using orally or intravenously administered isotopically labeled amino acids in space-flown and bed-rested individuals showed alterations in protein synthesis and degradation, with a net decrease in protein balance (47., 48., 49.). Taken together, these data suggest that changes in protein ...
The SR release sites are activated following the spread of electrical activity (Huxley and Taylor, 1958) along the transverse (T) tubular system (Eisenberg and Gage, 1967; Adrian et al. 1969a, b; Peachey, 1973) from the surface membrane (Bm). 展开全部 机器翻译 ...
, which may cause body115to be fastened to conventional fixation rod120. When tower110interferes with another tower110, associated with conventional assembly100, a false torque condition may be created (e.g., shown by the dashed curved arrow labeled False Torque Condition in FIG. 4A) in a ...
The tissue-resident skeletal stem cells (SSCs), which are self-renewal and multipotent, continuously provide cells (including chondrocytes, bone cells, marrow adipocytes, and stromal cells) for the development and homeostasis of the skeletal system. In r