In this embryo, in which the eye has been removed to reveal underlying tissues, only the dorsal (superior) oblique muscle was labeled. The sites of origin of extraocular muscles parallel the sites of emergence of the three cranial motor nerves that innervate them. However, in contrast to ...
(1993). Characterization of skeletal muscle actin labeled with the triplet probe erythrosin-5-iodoacetamide. Photochem. Photobiol. 58, 858-866.Ludescher RD, Liu Z. Characterization of skeletal muscle actin labeled with the triplet probe erythrosin-5-iodoacetamide. Photochem Photobiol. 1993 Dec; 58 ...
Skeletal muscle makes up 40% of our body mass, is essential for movement and has pivotal roles in metabolism and immune regulation1,2,3. The major components of skeletal muscle, the multinucleated myofibers (MFs), are classified into ‘slow-twitch’ (type I) and ‘fast-twitch’ (type IIA...
In a typical study, labeled phenylalanine is infused intravenously over 8 h. Over the last 3 h, unlabeled amino acids are also infused. This provides additional substrate for muscle protein synthesis; normally, what is seen is a spike in synthetic rate. However, inevitably, muscle protein ...
In a typical study, labeled phenylala- nine is infused intravenously over 8 h. Over the last 3 h, unlabeled amino acids are also infused. This provides addi- tional substrate for muscle protein synthesis; normally, what is seen is a spike in synthetic rate. However, inevitably, mus- cle ...
labeled next to the graphs.cKinases in type IIb fibers with different expression profiles in the EDL, TA, and GAST; branched-chain ketoacid dehydrogenase kinase (BCKDK), phosphorylase b kinase regulatory subunit beta (PHKB), phosphorylase b kinase γ catalytic chain, skeletal muscle isoform (PHKG...
Fig. 5. Venn diagram illustrating the overlap of differentially expressed pathways in liver (A), WAT (B) or quadriceps muscle (C) between Ldlr−/−.Leiden mice receiving an exercise intervention vs. mice left untreated (blue circle), mice treated via a dietary switch vs. mice left untrea...
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17. SRPK3 is essential for muscle growth and homeostasis13,14,16, and skeletal muscle is highly sensitive to SRPK3 expression levels, as not only its deficiency but also its overexpression led to an abnormal muscle phenotype in mice, reminiscent of a human centronuclear myopathy16. In view ...
2). To selectively increase the number of MuSCs, FAPs and macrophages for clustering and downstream analysis, we used FACS to enrich for the three cell types mentioned as an alternative to sequencing whole muscle cell suspension (Fig. 1b, Supplementary Fig. 1). In addition to an overall ...