All muscle stem cells (except the ones forming the muscles of the head) arise from specific transient mesodermal structures of early embryos called dermomyotomes. Along embryonic, then foetal and post-natal development, these cells are specified by a combination of different signals. They respond ...
Muscles are linked to bones by tendons or tendon-like structures through which the forces and movements developed by muscle contractions are transmitted to the skeleton. Contractions of skeletal muscles provide the stability and power for all body movements. Thus, any impairment in skeletal muscle ...
Include all relevant ions, structures, and processes in the explanation. How would you explain the skeletal muscle cell contraction were there no tubules? Explain function of skeletal muscle and how its cell supports the skeletal muscle function. Using striated muscle as ...
These techniques have led to the engineering of bioartificial muscles (organoids), which display many of the characteristics of in vivo muscle, including parallel arrays of postmitotic fibers organized into fascicle-like structures with tendon-like ends. They are contractile, express adult isoforms of...
Furthermore, we document the function of aging muscle microenvironment in immune cell attraction. Overall, we present a comprehensive human skeletal muscle aging resource (https://www.muscleageingcellatlas.org/) together with an in-house mouse muscle atlas to study common features of muscle aging ...
Muscle cells contain the organelles typically associated with eukaryotic cells; however, some muscle cell structures merit attention. The prefix ‘sarco’ is derived from the Greek word for flesh and is often used to denote certain muscle cell structures, including the sarcolemma (cell membrane), sa...
(non-myogenic cells and molecular structures) in the regulation of skeletal muscle regeneration. Myogenic cell environment includes inflammatory cells and particularly macrophages, vessel cells (endothelial and peri-endothelial cells) and interstitial cells. We aim at understanding the interactions between ...
The muscle cell cytoskeleton consists of proteins or structures whose primary function is to link, anchor or tether structural components inside the cell. Two important attributes of the cytoskeleton are strength of the various attachments and flexibility to accommodate the changes in cell geometry that...
muscle also has important sensory structures calledstretch receptors, which monitor the state of the muscle and return the information to the central nervous system. Stretch receptors are sensitive to the velocity of the movement of the muscle and the change in length of the muscle. They complete...
Based on the histological appearance, the injected muscle-derived cells not only delivered bmp, but may also actively participate in the bone formation. Some of the cells are entrapped within lacunae-like structures implying that they formed the surrounding osteiod. We cannot rule out, however, ...