A. has a prolonged plateau phaseB. spreads inward to all parts of the muscle via the T tubulesC. causes the immediate uptake of Ca2+ into the lateral sacs of the sarcoplasmic reticulumD. is longer than the actio
( 1971 ). Action potential generation in denervated rat skeletal muscle. Part II. The action of tetrodotoxin . Acta physiol. scand. , 82 , 70 – 78 .Redfern, P, Thesleff, S (1971) Action potential generation in denervated rat skeletal muscle II. The action of tetrodotoxin. Acta ...
Section “Biophysical stimulations for iPSC skeletal muscle differentiation” describes the biophysical stimuli that have been applied or could be applied to iPSCs to pursue skeletal muscle tissue engineering. Section “Challenges in the clinical translation of iPSC-derived skeletal muscle”, the challenge...
The skeletal muscle regeneration occurs in two main overlapping phases: the degeneration (necrosis) and reconstruction (Fig. 1) [9]. The course of them is similar in different organisms (e.g., mouse, rat, and human), regardless of the injury type [10,11]. Initiation of muscle degeneration...
Accordingly, short phases of repolarization are required for sustained tetanic contractions. Thus, in contrast to cardiac muscle, where this effect is not present because of the long action potentials and the inability to generate tetanus, larger contractile force in skeletal muscles could be generated...
showing EVs concentrated in the muscle interstitium, attached to extracellular matrix (ECM)-like structures by transmission electron microscopy [46]. Within muscle, satellite cell-derived EVs have been previously shown to influence early phases of myofiber growth in response to overload by regulating ...
initial length of muscle prior to contraction -overlap of thick and thin filaments -number of crossbridges 4 load lifted by the muscle when it shortens 本學習集中的詞語(24) period of time from action potential to onset of contraction
To better understand the changes underpinning this disease, we assessed whole-body energy homeostasis, skeletal muscle fatty acid metabolism, lipolysis in adipose tissue, and the skeletal muscle lipidome using young adult dysferlin-deficient male BLAJ mice and age-matched C57Bl/6J WT mice. BLAJ ...
Aberrant regeneration or fibrosis in muscle is the denouement of deregulated cellular and molecular events that alter original tissue architecture due to accumulation of excessive extracellular matrix. The severity of the insult to the skeletal muscle de
Patients with pancreatic cancer commonly develop weight loss and muscle wasting. Whether adipose tissue and skeletal muscle losses begin before diagnosis and the potential utility of such losses for earlier cancer detection are not well understood. We quantify skeletal muscle and adipose tissue areas fro...