During early phases of muscle development, skeletal muscle precursor cells align and fuse into multinucleated cells, termed “muscle fibers,” which run parallel to one another, along the longitudinal axis of the muscle (Fig. 7.1A). The contractile muscle fibers are ensheathed by variety of extr...
myotoniaperiodic paralysisskeletal muscle modelslowfast oscillations.Medical research has indicated that abnormalities of skeletal muscles, myotonia and periodic paralysis, are caused by alteration in the voltage-gated sodium channels. This assumption led to studies of channel behavior based on the dynamics...
and S. Thesleff, Action potential generation in denervated rat skeletal muscle. I. Quantitative aspects. Acta physiol. scand. 1971. 81. 557–564. Action potential generation was studied at various periods up to one week after denervation in individual muscle fibres of the extensor digitorum ...
Section “Biophysical stimulations for iPSC skeletal muscle differentiation” describes the biophysical stimuli that have been applied or could be applied to iPSCs to pursue skeletal muscle tissue engineering. Section “Challenges in the clinical translation of iPSC-derived skeletal muscle”, the challenge...
Accordingly, short phases of repolarization are required for sustained tetanic contractions. Thus, in contrast to cardiac muscle, where this effect is not present because of the long action potentials and the inability to generate tetanus, larger contractile force in skeletal muscles could be generated...
Initiation of an action potential in skeletal muscle by stimulating its motor nerve A. requires the release of NE B. requires spatial facilitation C. requires temporal facilitation D. requires the release of acetylcholine 如何将EXCEL生成题库手机刷题 如何制作自己的在线小题库 > 手机使用 分享...
Thus, the dysregulation of each of these phases by alterations occurring in SC epigenome results in abnormal myogenic progress and incapacity to properly regenerate muscle. The epigenetic modifications include several aspects (Figure 1): DNA methylation, especially CpG methylation, DNA demethylation, ...
skeletal muscle; NLRP3; inflammasome; pyroptosis; metabolic syndrome; sepsis; critical limb ischemia; mmyotrophic lateral sclerosis; myopathies Graphical Abstract1. The NLRP3 Inflammasome 1.1. NLRP3 Inflammasome Actors Sterile inflammation drives the pathogenesis of various diseases and is controlled by ...
During early phases of muscle development, skeletal muscle precursor cells align and fuse into multinucleated cells, termed “muscle fibers,” which run parallel to one another, along the longitudinal axis of the muscle (Fig. 7.1A). The contractile muscle fibers are ensheathed by variety of extr...
Effects of short‐term training on insulin sensitivity and skeletal muscle glucose metabolism in Standardbred horses (2009) Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle. Diabetologica 52, 891-900. Treiber, K.H., Hess,... L Stewart‐Hunt,RJ Geor...