In metaphase, the sister chromatids move towards the opposite poles of the spindle. View Solution Which is unique to mitosis and does not occur in meiosis ? View Solution During meiosis, crossing over occurs between View Solution The events shown below occur during different phases - ...
The spindle poles move apart, elongating the cell. This elongation creates space for the sister chromatids to be physically pulled toward opposite ends. As anaphase progresses, the separated sister chromatids reach their respective spindle poles. Once they have reached the poles, the spindle apparatu...
When all pairs of sister chromatids have achieved bivalent attachment, an event monitored by the spindle assembly checkpoint, anaphase is triggered, the linkage between sisters is dissolved, and the two sets of chromatids move to opposite poles. Chromosome-microtubule attachment is best understood in...
Forces in the spindle are crucial for the incorporation of chromosomes into the spindle and the segregation of sister chromatids. Even though we did not directly measure these forces, we used the shape of the spindle and the elastic properties of MTs to estimate the forces at the kinetochore ...
Mitosis and meiosis both rely on cohesin, which embraces the sister chromatids and plays a crucial role for the faithful distribution of chromosomes to daughter cells. Prior to the cleavage by Separase at anaphase onset, cohesin is largely removed from c
chromosomes began to leave the metaphase plate and move toward the spindle poles (Figure 4Aand Supplemental Movie S1 onCellwebsite), reflecting premature disjunction and segregation. The phenotype gradually became more severe, as more chromatids left the plate and moved polewards. In contrast, cont...
Metaphase cells have short spindles for efficient bi-orientation of chromosomes. The cohesin proteins hold sister chromatids together, creating Sister Chromatid Cohesion (SCC) that helps in the maintenance of short spindle lengths in metaphase. The buddi
4c). We expect the crosslinkers to accumulate all along the interface between the bridging fibre and the k-fibre, rather than predominantly at the junction. Note that during metaphase kinetochores move and k-fibres grow and shrink; thus, the junction may also move. For example, kinetochores ...