Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage In yeast, anaphase entry depends on Pds1 proteolysis, while chromosome re-duplication in the subsequent S-phase involves degradation of mitotic cyclins suc... Gabriela,Alexandru,...
Mitotic sister chromatid separation: what Drosophila mutants can tell us. Trends Cell Biol. 8 : 150. [ PubMed ]Philp, A. V., 1998. Mitotic sister chromatid separation: what Drosophila mutants can tell us. Trends Cell Biol. 8 : 150....
EMBO Gold Medal Review 2006 What is your assay for sister-chromatid cohesion ?Uhlmann, Frank
During anaphase, the “upward phase,” the cohesin proteins degrade, and the sister chromatids separate at the centromere. Each chromatid, now called a chromosome, is pulled rapidly toward the centrosome to which its microtubule is attached. How does segregation happen during anaphase 2? There are...
Phase 2: Metaphase Metaphase is the second phase of mitosis. During metaphase, spindle fibers attach to thecentromereof each pair of sister chromatids. The sister chromatids also move into the middle of the cell and line up along an invisible line, called themetaphase plate. These spindle fibe...
Following metaphase proper (discussed in detail shortly) isanaphase. This is the shortest phase, and in it, the sister chromatids are pulled apart by the spindle fibers at their centromeres and drawn toward the oppositely positioned centrosomes. This results in the formation of daughter chromosomes...
Sister chromatids pulling apart. Video footage fromVisible Biology. Telophase is the final phase of mitosis, and this is when the official division of one cell into two happens. First, the chromosomes relax back into chromatin and a nuclear envelope forms around each chromatin blob, making it ...
(1) G1 phase: mother centriole initiates formation of the primary cilium; (2) S phase: each centriole templates the assembly of a single daughter centriole, which grows from its proximal base and remains tightly bound, or "engaged," until disengagement occurs at mitosis; (3) G2 phase: ...
(CYCD3;1) triggers a quick transition into the mitotic cycle, reducing the proportion of cells in the G1 phase of the cell cycle, and decreasing cell size [163,164]. In contrast, slowing division with a dominant negative form of theCYCLIN DEPENDENT KINASE A;1(CDKA;1) increases final ...
The sister chromatid exchange assay: what does a positive result mean?doi:info:doi/10.1016/S0278-6915(97)85463-4XingELSEVIERFood & Chemical Toxicology