Fibroblasts, which are derived from mesenchymal stem cells (MSCs), can be distinguished from epidermal cells, epithelial cells, and leukocytes [14,15]. CAFs are the predominant cell type in the TME and play a tumorigenic role. They contribute to the survival and proliferation of tumor cells, b...
mutation N 1325 S in cardiac sodium channel gene SCN 5 A causes cardiomyocyte apoptosis , cardiac fi brosis and contractile dysfunction in micea Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA b Center for Cardiovascular Genetics/NE40, Lerner ...
In control larvae grown in standard food, autophagosomes were barely detected, whereas autophagy induction by starvation led to the formation of acidic autolysosomes, which could be visualized only in the red channel, due to GFP quenching. In fed D-iduaRNAi3 larvae, we observed the formation of...