SINGLE-STRANDED RNA MOLECULE FOR GENE EXPRESSION CONTROLPROBLEM TO BE SOLVED: To provide a new nucleic acid molecule suppressible of gene expression.OKI TADAAKI大木 忠明HAYASHI HIROTAKE林 宏剛HAMAZAKI TOMOHIRO濱崎 智洋SHIRAMIZU HISAO白水 久男...
Electrical detection of RNA cancer biomarkers at the single-molecule level Keshani G. Gunasinghe Pattiya Arachchillage Subrata Chandra Juan M. Artes Vivancos Scientific Reports (2023) Charge transport in individual short base stacked single-stranded RNA molecules Subrata Chandra Ajoke Williams Juan...
Drosophila Dicer-2 (Dcr-2) produces small interfering RNAs from long double-stranded RNAs (dsRNAs), playing an essential role in antiviral RNA interference. The dicing reaction by Dcr-2 is enhanced by Loquacious-PD (Loqs-PD), a dsRNA-binding protein that partners with Dcr-2. Previous biochemi...
Presence of vertically transmitted double-stranded RNAs in many healthy fungi, algae and higher plants. 2. Occurrence of these double-stranded RNAs in structures which either resemble the replication complexes of positive-stranded RNA viruses or the protein shells of double-stranded RNA viruses. 3. ...
An aptamer is a relatively short stretch of single-stranded DNA, RNA, or polypeptide that can bind to the corresponding ligand with high affinity and strong specificity. From:Materials Today,2019 About this page Set alert Chapters and Articles ...
Single-molecule, motion-based DNA sequencing using RNA polymerase. We present a method for sequencing DNA that relies on the motion of single polymerase molecules. When a given nucleotide species limits the rate of , polym... WJ Greenleaf,SM Block - 《Science》 被引量: 243发表: 2006年 Splic...
Small molecule-RNA interaction: spectroscopic and calorimetric studies on the binding by the cytotoxic protoberberine alkaloid coralyne to single stranded ... RNA has attracted recent attention for its key role in gene expression and hence targeting by small molecules for therapeutic intervention. This ...
deoxyribonucleic acid: an extremely long, double-stranded nucleic acid molecule arranged as a double helix that is the main constituent of the chromosome and that carries the genes as segments along its strands: found chiefly in the chromatin of cells and in many viruses. ...
The Flaviviridae genome is a plus-stranded RNA molecule that is translated into a unique polyprotein which is subsequently processed by viral and host proteinases into 10 mature viral proteins: three structural (capsid, premembrane, and envelope proteins) and seven non-structural proteins (NS1, NS2...
First, we sought to develop a method to visualize miRNA-mediated mRNA decay with single-molecule resolution. In human U2OS cells, which have been widely used for RNA imaging20,21,22, miR-21 is the most abundant miRNA23(Supplementary Fig.1a–c). Thus, we constructed the reporter system that...