In the past several decades, maintenance and replacement problems of deteriorating systems have been extensively studied in the literature. Thousands of ma... H Wang - 《European Journal of Operational Research》 被引量: 1945发表: 2002年 UNIT ACTIVITY CONNECTED WITH MOVEMENT INITIATION AND AROUSAL ...
Existing computational methods that use single-cell RNA-sequencing (scRNA-seq) for cell fate prediction do not model how cells evolve stochastically and in physical time, nor can they predict how differentiation trajectories are altered by proposed inter
We next analyzed the inference of cell fate decision governed by TF activity and found TFs differentially expressed for both fates, whereRunx3andNfiaare pro-proprioceptors andPou6f2, Nr5a2, Hoxb5, Egr1 and Junbare pro-mechanoreceptors (Fig.3dand Source Data file). Interestingly,NfiaandNr5a2...
A preliminary experiment showed that the activity of ZXR-1 on both Hela and HepG2 cells reached the peak after 6 h of incubation, while ZXR-2 activity achieved the peak after 2 h (Figs. 2 and S3). Thus, the IC50 values of ZXR-1 and ZXR-2 were determined after 6 h and 2 h of...
Companies considering purchasing an AI cluster must factor utilization at the heart of their calculations. What cluster capacity is needed, and how much will it be used for value-adding activity over its lifetime? The answers to these questions are not easy to determine, as they are affected ...
activity with only 30 mV overpotential at 10 mA cm−2toward HER [161]. Similarly, Chen’s group reported a general and facile synthesis approach to fabricate a series of SACs by a simultaneous self-reduction-stabilization process under ambient conditions using 2D Ti-vacancy-rich Ti3−xC2Ty...
BMP activity is required for tooth development from the lamina to bud stage J Dent Res, 91 (2012), pp. 690-695 CrossrefView in ScopusGoogle Scholar [6] E. Järvinen, M. Tummers, I. Thesleff The role of the dental lamina in mammalian tooth replacement J Exp Zool Part B: Mol Dev ...
Since, YrbE1A has been predicted to be a transmembrane protein [20], so the observed polymorphism in its gene may influence activity of the protein. From the computational analysis, we could infer that the results obtained on the basis of structural details (PolyPhen) and sequence details (...
et al. Coupled scRNA-Seq and intracellular protein activity reveal an immunosuppressive role of TREM2 in cancer. Cell 182, 872–885.e19 (2020). Article CAS PubMed Google Scholar Frangieh, C. J. et al. Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of ...
Together, this suggests a largely homeostatic replacement of sheath numbers after single-cell demyelination. Notably, while on average the internodes that were formed after cortical remyelination were shorter than the pre-existing ones (Fig. 2e), they were longer than the new internodes formed by...