Antibiotic treatment generally results in the selection of resistant bacterial strains, and the dynamics of resistance evolution is dependent on complex interactions between cellular components. To better characterize the mechanisms of antibiotic resista
CellRank 2: unified fate mapping in multiview single-cell data Philipp Weiler Marius Lange Fabian Theis Nature Methods (2024) Engineered platforms for mimicking cardiac development and drug screening Madison Stiefbold Haokang Zhang Leo Q. Wan Cellular and Molecular Life Sciences (2024)Download...
Why do we need quality-assured diagnostic tests for sexually transmitted infections? The bacterial sexually transmitted infections (STIs) syphilis, gonorrhoea and chlamydia can all be cured with a single dose of antibiotic. Unfortunately, h... RW Peeling,D Mabey,A Herring,... - 《Nature Reviews...
Antibiotic susceptibility tests showed that 44 (96%) of the 46 non-PPNG strains tested had MICs of piperacillin of 2 mg/l or less and 26 (76%) of the 34 PPNG strains had MICs of 32 mg/l or more. This regimen is not recommended for use as first line treatment in areas where ...
Current STI treatment guidelines recommend either azithromycin 1 g single dose or doxycycline 100 mg twice daily for 7 days for the treatment of rectal chla- mydia [15–18]. However, there has been increasing con- cern about the effectiveness of azithromycin for rectal chlamydia with ...
Current STI treatment guidelines recommend either azithromycin 1 g single dose or doxycycline 100 mg twice daily for 7 days for the treatment of rectal chlamydia [15–18]. However, there has been increasing concern about the effectiveness of azithromycin for rectal chlamydia with observational studies...
Prompt treatment of sexually transmitted infections (STIs) with effective antibiotic regimens preferably contained in a single supervised dose is a cornerstone of STI control. The World Health Organization (WHO) revised its treatment guidelines in 2001.1 A variety of regimens is proposed from which ...
The first follow-up examination for all patients was between post-intervention days 2 and 3. The second follow-up examination was between day 15 and 30 following biopsy. Urine was cultured in all cases and any adverse drug reactions (ADRs) related to the antibiotic treatment were noted. We ...
Dalbavancin Use in Vulnerable Patients Receiving Outpatient Parenteral Antibiotic Therapy for Invasive Gram-Positive Infections. Infect. Dis. Ther. 2019, 8, 171–184. [Google Scholar] [CrossRef] [PubMed] [Green Version] Bryson-Cahn, C.; Beieler, A.M.; Chan, J.D.; Harrington, R.D.; ...
Accurate and rapid diagnostics simultaneously predicting antibiotic susceptibility and diagnosis may help address this challenge. We report early data from a novel approach using single gene targeted nanopore sequencing for simultaneous STI identification and AMR detection among female sex workers (FSWs) in...