In 2012, a randomised controlled trial in Papua New Guinea showed that oral azithromycin was as effective as parenteral penicillin in the treatment of active yaws.6 On the basis of this finding, WHO adopted a revised strategy of treatment with single-dose azithromycin for all community members in...
Single Dose Compared to Multi Dose Metronidazole for the Treatment of Trichomoniasis in Women: A Meta-AnalysisKissinger, Patricia
Home > Section > Chapter O'Farrell, N. Transactions of the Royal Society of Tropical Medicine and Hygiene 84(6): 862 1990 ISSN/ISBN:0035-9203 2151409 10.1016/0035-9203(90)90109-r 002107223 Article/Abstract emailed within 0-6 h Payments are secure & encrypted ...
Current treatment guidelines recommend either azithromycin 1 g single dose or doxycycline 100 mg twice daily for 7 days. However, there are increasing concerns about treatment failure with azithromycin. We are conducting the first randomised controlled trial (RCT) to compare treatment efficacy of ...
Single-dose treatment of trichomonal vaginitis: a comparison of tinidazole and metronidazole. A randomized, comparative trial was carried out in 100 patients with trichomonal vaginitis to compare the efficacy and toleration of a single 2 g dose of t... R Anjaneyulu,SA Gupte,DB Desai - 《Journ...
We measured the morphologic and contractile phenotypes of cells before and after one-hour treatment with a physiologic dose of Mavacamten. Fig. 8: Mavacamten treatment affects contractile function in single hiPSC-CM within one hour. a Bar plots showing a consistent increase single cells area ...
(Luminal-C)) marked byTacstd2,Ck4andPscaexpression. Luminal-C cells located at the distal prostate invagination tips (termed Dist-Luminal-C) exhibited greater capacity for organoid formation in vitro and prostate epithelial duct regeneration in vivo. Lineage tracing of Luminal-C cells indicated ...
At each dose level the volunteer, but not the investigator, was blinded to treatment allocation. This study was conducted in accordance with the Declaration of Helsinki and the International Conference on Harmonisation's Guidance for Good Clinical Practice, and ethics approval was obtained from the ...
Crucially, methods to quantify the cytosolic concentration of a delivered siRNA have been lacking7 and the dose-response relationship for cytosol-delivered siRNA has not been clear. As a consequence, it has generally not been possible to determine delivery efficiencies, and the scope for improvement...
for understanding MPAL tumor heterogeneity and response to chemotherapy and suggest that the broad adoption of such technologies for monitoring cancer progression (and tailoring treatment) is within reach. In summary, scRNA-seq provides unparalleled insight into cell heterogeneity but remains underutilized...