1) Explain transcription and translation in detail 2) Explain DNA replication 3) Explain epigenetics Explain fully how DNA is replicated. Discuss the process of DNA replication. How DNA replication occurs? Explain the functions of all enzymes involved in the replication of DNA. Describe how DNA re...
Antagonistic pleiotropy is often blamed for senescence and aging, as research has found that the body begins to shift resources away from properDNAtranscription and repair as we get older, a “decision” controlled and triggered by pleiotropic genes. Those resources are instead used for other forms...
Triplex DNATriplex-Forming OligonucleotidesRegulation of Gene ExpressionNucleoside AnalogAntigeneInhibition of TranscriptionThe term "simple location" was coined by Alfred North Whitehead, in his book Science and the Modern World.1 It is a fallacy of simple location to attempt to locate concrete ...
Within biological systems, several activities involving the basic units of a gene take place. Such processes as DNA replication, and RNA translation and transcription into proteins must be controlled; otherwise, the systems could yield numerous destructive or useless gene products. Transcriptional control...
How do genes of two parents influence the traits of an offspring? Genes inherited on the X chromosomes code for traits. Assume the gene for freckles is recessive (f). A woman without freckles has a son that does have freckles. Write a det...
The development and progression of NAFLD are associated with many factors, and the “multiple-hit” hypothesis provides a more accurate explanation of NAFLD pathogenesis than other hypotheses. The “multiple-hit” hypothesis considers the combined actions of multiple insults in genetically predisposed subj...
However, it is notable thatPTHrPknockout mice have normal beta-cell mass as compared to controls, suggesting that PTHrP may not be crucial for normal beta-cell massin vivo.However, the explanation of this result should be found on the possibility that the PTHrP was absent in islets but it ...
Taken together, these results indicate that key genes responsible for the FBP have a higher expression level in the purple-flesh tubers of yam. This finding is an important explanation of well-known higher antioxidant activity in pigmented tissues found in a number of tissues. Identification of ...
1). Based on this observation, one possible explanation for the widespread use of interaction domains is that they allow for the rapid evolution of new signaling pathways, by the incorporation of a novel interaction domain into a pre-existing polypeptide. For example, yeast have no functional SH...
Figure 1. The Consequences of CDK4/6 Inhibition The four cellular mechanisms, labeled A–D, that contribute to the efficacy of CDK4/6 inhibitors are shown. Details are provided in the accompanying text. However, a number of recent investigations provide an alternative mechanistic explanation for ...