Microorganisms can be unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). They include bacteria, archaea, fungi, protozoa, algae, and viruses. Bacteria are single-celled microbes that lack a nucleus. Archaea are like bacteria, but they have different structures an...
lateral geniculate nucleus inputs to a simple cell must be supplemented by a component of feedforward inhibition that is untuned for orientation and responds to high temporal frequencies to explain the sharp contrast-invariant orientation tuning and low-pass temporal frequency tuning of simple cells....
et al. Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein. Mol. Cell. Biol. 26, 9003–9015 (2006). CAS PubMed PubMed Central Google Scholar Guillemot, L. et al. Cingulin is dispensable for epithelial ...
Cells, 13(8), 721. https://doi.org/10.3390/cells13080721 Article PubMed PubMed Central CAS Google Scholar Ziehm, M., Piper, M. D., & Thornton, J. M. (n.d.). Analysing variation in Drosophila aging across independent experimental studies: a meta‐analysis of survival data. https:/...
Expression of mutant Smp proteins lacking either the nuclear localization signal or the β-catenin interaction domain reveal that the translocation of Smp into the nucleus is essential for β-catenin nuclear localization and Wnt signaling in vivo. We also provide evidence that mammalian Smp is ...
While most of the remaining Hydra Bcl-2-like proteins had no effect when transfected into HEK293T cells, HyBcl-2-like 5 did exhibit a weak pro-apoptotic effect. To analyze the anti-apoptotic effect of Hydra Bcl- 2 family members, we transfected HEK293T cells with plasmids encoding Hydra ...
Autophagy is a cellular process that involves the degradation of cellular components, which is triggered in cells during periods of nutrient deprivation or cellular stress [1]. The autophagy process consists of four essential stages: initiation, nucleation, maturation, and degradation [2]. The far-...
Many people are overfed but malnourished, lacking the essential nutrients their cells need to function optimally. It’s not about restrictive diets but providing the body with the right nutrients. We need certain nutrients in order to make our cells function. This approach encourages a more intuit...
and thus allows NTRs to return “alone” to the starting compartment for the next round of transport. Such transport cycle transfers one Ran molecule from the nucleus to the cytoplasm. Nuclear transport factor 2 (NTF2) returns Ran to the nucleus and thus has to pass NPCs more frequently than...
The ability to analyze protein function in a native context is central to understanding cellular physiology. This study explores whether tagging endogenous proteins with a reporter is a scalable strategy for generating cell models that accurately quantit