Silymarin exerts antifungal effects via membrane- targeted mode of action by increasing permeability and inducing oxidative stress. Biochim Biophys Acta. 2017;1859(3):467-74.Yun, D.G.; Lee, D.G. Silymarin exerts antifungal effects via membrane-targeted mode of action by increasing permeability ...
These recommendations aim to provide deeper insights into silymarin’s mode of action and its potential as a functional food product. By addressing these recommendations, future studies can build upon the findings of this research and contribute to the advancement of knowledge in the field of ...
Herbal remedies for liver fibrosis: A review on the mode of action of fifty herbs Journal of Traditional and Complementary Medicine Journal2018,Journal of Traditional and Complementary Medicine UzmaLatief,RiazAhmad 4.1Silymarin Silymarinis a flavonoid complex consisting ofsilybin,silydianinand silychrisin...
Milk thistle (Silybum marianum fruits) has been recently proposed to be used by nursing mothers for stimulating milk production; however, the mode of action of this herbal drug is still unknown. In this paper, we have evaluated the effect of a micronized standardized extract of S. marianu...
This review examines the pharmacology, mode of action, efficacy and safety of silymarin compounds in chronic liver diseases with a particular emphasis on a systematic review of its effects in patients with chronic viral hepatitis B and C. SEARCH METHODS OF REVIEW The literature search engines Pub...
The re-emergence of silymarin as a natural remedy for diseases of the liver and biliary tract necessitates revaluation of the efficiency of this compound and its possible mode of action. The aim of this study was to investigate the potentials of silymarin on the amelioration of hepatic injuries...
Atomic force microscopy (AFM) The morphological examination of the nanoparticles was carried out using a AFM setup. Smnp suspensions (100 µL) from different preparations were deposited onto fused mica substrates and the particles were visualized in tapping mode using RTESP tips (Veeco, Santa ...
Another possible mode of action of this plant against cancer would be to stimulate apoptosis or natural death of damaged cells.Does milk thistle infusion have these properties? It is important to mention that milk thistle infusions have very little silymarin, because these components are poorly solu...
At the molecular level, silymarin, an efficient radical scavenger itself, modulated VEGF, Hif1a and several inflammatory cytokines indicating an integrated mode of action which is rarely observed in any other antioxidants further suggesting its pluripotency against hypobaric hypoxia. Competing interests The...
aureus, was further investigated for the mode of its interaction with the efflux pumps. For this purpose, S. aureus with the induced expression of efflux pumps was incubated with ethidium bromide and baicalein, a known inhibitor of both NorA and MepA efflux pumps, resulting in the accumulation...