Silybin is recognized as the primary bioactive component, constituting 50–70% of the extract, and commercial supplements are often standardized based on its content.[1][2][3][4] What are silymarin’s main benefits? Silymarin has a historical application in treating several liver disorders (e....
Silymarin, Milk Thistle supplerment for Liver protection against liver damage. Silymarin case study about liver cirrhrosis, hepatitis B and hepatitis C.Health Benefits and Side Effects
Flavonoidsin general are plant metabolites that possess many health benefits.Silymarin, a combination ofsilybinA, silybin B, isosilybin A, isosilybin B,silychristinA,silydianin, andtaxifolin, isolated frommilk thistle(Silybum marianumL. Gaertn., Asteraceae) has shown protective action of β-cell in...
Uses, benefits, Side Effects Protect liver. Hepatoprotective effect.Antioxidation.The phenolic hydroxyl group of silymarin provides hydrogen atoms and has a strong antioxidant effect. They have the characteristics of scavenging free radicals and anti-lipid peroxide activit...
Merging clinical phenotypes of fatty liver disease (NAFLD/MAFLD, NASH, DILI, ALD) into a single basket entity, toxic liver diseases (TLDs), based on common pathomechanism will allow clinicians to evaluate the benefits of silymarin as an antioxidant and potential hepatoprotective agent. The limited...
has been observed that the concentrations required for many of the known pharmacological effects of silymarin are hardly achievable in both animals (~0.73%)8and humans (~1–2%)9. Thus, the action mechanisms of silymarin and its hepatoprotective benefits warrant further elucidation. Of interest, ...
It has been particularly recognized for its potential benefits in conditions related to the heart, liver, kidneys, and Vol:.(1234567890) Discover Applied Sciences (2024) 6:617 | https://doi.org/10.1007/s42452-024-06231-3 Research gall bladder [19]. The plant is native to China, South ...
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Many recent studies have scientifically investigated the use of natural-derived components or micronutrients, and their potent benefits on human health [1], [2]. Plant-derived compounds have been reported to target various cellular processes at a molecular level [3]. Currently, there are more than...
Silymarin is also well known to exert anti-inflammatory, antitumor, and antidiabetic effects [11], [12]. Recently, animal and human studies with silymarin are increasingly being carried out, and the hepatoprotective effects of silymarin have been demonstrated with minimal side effects in these ...