Silk-elastinlike protein polymer hydrogels:Influence of monomer sequence on physicochemical properties. Ramesh D,Arthur V C,Robert Bet al. Polymer . 2009Dandu R, Von Cresce A, Briber R, Dowell P, Cappello J, Ghandehari H (2009) Silk-elastinlike protein polymer hydrogels: Influence of ...
Comparison of silk- elastinlike protein polymer hydrogel and poloxamer in matrix-mediated gene delivery. Int J Pharm. 2012; 427(1):97-104. [PubMed: 21982738]Price R, Gustafson J, Greish K, Cappello J, McGill L, Ghandehari H. Comparison of silk-elastinlike protein polymer hydrogel and ...
Costa2, Susana R. Chaves1, Raul Machado1, Margarida Casal1 & Tony Collins1 Silk-elastin-like proteins (SELPs) are a family of genetically engineered recombinant protein polymers exhibiting mechanical and biological properties suited for a wide range of applications in the biomedicine...
Silk-elastinlike proteinnanogelthermoresponsivedrug deliverymatrix-metalloproteinaseSilk-elastinlike protein polymers (SELPs) self-assemble into nanostructures when designed with appropriate silk-to-elastin ratios. Here, we investigate the effect of insertion of a matrix metalloproteinase-responsive peptide ...
Silk-elastin-like proteins (SELPs) combining the physicochemical and biological properties of silk and elastin have a high potential for use in the pharmaceutical, regenerative medicine and materials fields. Their development for use is however restraine
Recently, a series of genetically engineered silk-elastin-like protein (SELP) hydrogels have developed. Their mechanical and optical properties can dynamically respond to multi-stimuli, including temperature, ionic strength, pH and so on, based on protein folding and unfolding at the molecular level ...
Silk-elastin-like protein polymers (SELPs) combine the mechanical and biological properties of silk and elastin. These properties have led to the development of various SELP-based materials for drug delivery. However, SELPs have rarely been developed into nanoparticles, partially due to the complicat...
Hydrophobic drug-triggered selfassembly of nanoparticles from silk-elastin-like protein polymers for drug delivery. Biomacromolecules, 2014, 15: 908–914 Google Scholar Guziewicz N, Best A, Perez-Ramirez B, et al. Lyophilized silk fibroin hydrogels for the sustained local delivery of therapeutic ...
Moreover, The SELP (silk-elastinlike protein polymer)-controlled gene delivery approach could potentially improve activity of adenoviral-mediated gene therapy of head and neck cancer and limit viral spread to normal organs at the same time[12]. It has been known that the properties of silk-...
Elastin-like polypeptides, such as oligomeric repeats of the pentapep- tide VPGXG, exhibit reversible and inverse phase transitions with varying temperatures.24 Recombinant spider silk proteins can be isolated by extraction with organic acids, such as formic acid and propionic acid.25 We found that...