Silk-elastin-like proteins (SELPs) are a family of genetically engineered recombinant protein polymers exhibiting mechanical and biological properties suited for a wide range of applications in the biomedicine and materials fields. They are being explored as the next generation of biomaterials but low ...
Silk-elastinlike protein-based hydrogels for delivery of bioactive agents and as liquid embolics. A range of bioactive agents, from low molecular weight drugs to adenoviral vectors can be released from the hydrogels. The use of these polymers as liquid embolics is shown in both embolization of ...
正在加载 Silk-elastinlike protein polymers for matrix-mediated cancer gene therapy. Adv. Drug Deliver. Rev. Pub Date : 2010 Dec 3DOI : 10.1016/j.addr.2010.04.006 Joshua A. Gustafson , Hamidreza Ghandehari Silk-elastinlike protein polymers (SELPs) are recombinant polymers designed from silk ...
Costa2, Susana R. Chaves1, Raul Machado1, Margarida Casal1 & Tony Collins1 Silk-elastin-like proteins (SELPs) are a family of genetically engineered recombinant protein polymers exhibiting mechanical and biological properties suited for a wide range of applications in the biomedicine...
One unique class of genetically engineered biomaterials is the family of silk–elastinlike protein polymers (SELPs) [2]. SELPs are block copolymers composed of alternately repeated silk (GAGAGS) and elastinlike (GVGVP) units. Elastin units confer aqueous solubility and silk units provide ...
Effect of an artificial silk elastin-like protein on the migration and collagen production of mouse fibroblasts. J Biomater Sci Polym Ed. 2014;25:1266–77. Article CAS PubMed Google Scholar Kawai K, Kanda N, Kawabata S, Suzuki S. The effect of silk-elastin in the pressure ulcers. Japan...
Silk-elastin-like proteins (SELPs) combining the physicochemical and biological properties of silk and elastin have a high potential for use in the pharmaceutical, regenerative medicine and materials fields. Their development for use is however restraine
The silk-elastinlike class of genetically engineered protein polymers is composed of tandemly repeated silk-like (Gly–Ala–Gly–Ala–Gly–Ser) and elastin-like (Gly–Val–Gly–Val–Pro) amino acid blocks. The precision with which these polymers can be synthesized, as well as the ability to ...
ADF, Araneus diadematus Fibroin; CPP, Cell Penetrating Peptide; MaSp, Major Ampullate Spidroin; NCAM, neural cell adhesion molecule; SELP, silk-elastin-like polymer with silk-like units (GAGAGS)x and elastin-like units (GVGVP)y; R5 domain derived from a silaffin protein; Tat protein: trans...
Teng et al., “Physical Crosslinking Modulates Sustained Drug Release from Recombinant Silk-Elastinlike Protein Polymer for Ophthalmic Applications,” J. Control Release; 156(2):186-197; Dec. 10, 2011. Wu et al., “Impact of Sterilization Methods on the Stability of Silk Fibroin Solution,”...