Significance analysis of MicroarrayFalse discovery RateClusteringIJCSIMicroarray is the gene expression data that represent gene in different biological states. Methods are needed to determine the significance o
Statistical algorithms such as Significance Analysis of Microarrays (SAM) and hierarchal clustering have been developed to help facilitate analysis of gene expression data from microarrays. The SAM algorithm assigns a score to each gene represented on a microarray on the basis of change in gene ...
Gene Enrichment AnalysisGene expression profiling provides insight into the functions of genes at a molecular level. Microarray technology measures the relative activity of previously identified target genes. For understanding the disease network fundamentals of breast cancer, analysis of gene expression ...
Baty F, Jaeger D, Preiswerk F, Schumacher M, Brutsche M: Stability of gene contributions and identification of outliers in multivariate analysis of microarray data. BMC Bioinformatics. 2008, 9: 289-10.1186/1471-2105-9-289. Article PubMed Central PubMed Google Scholar Elo LL, Filén S, La...
Bioinformatical analysis, Microarray, Ovarian cancer, Differentially expressed geneOvarian cancer (OC) is the highest frequent malignant gynecologic tumor with very complicated pathogenesis. The purpose of the present academic work was to identify significant genes with poor......
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2.11. RNA microarray data analysis upon TRIB3 silencing in MCF-7 breast cancer cells Differentially expressed analysis for the GSE116671 expression matrix was conducted using the "limma" R package. The result was visualized as a volcano plot using the "ggplot" R package. Subsequently, the "clus...
types (frequency 45.0%) for haplotype-based association We observed two LD blocks of ANKK1 in AAs, which were analysis. different from those in EAs. In addition, three LD blocks of DRD2 observed in the EA sample were not found in the AA Vector Construct sample. Notably, the rs1800497 ...
of the PCR data confirmed that the gene cluster was significantly enriched among CC2. Comparative sequence analysis of the flanking regions suggests that the gene cluster is located in the HH22 and TX0104 versions of theE. faecalispathogenicity island [36]. Recently, a microarray-based assessment...
We excluded closely located miRNA and gene pairs (defined as physical distances between the miRNA and gene below 1 Mbp), as the genome-wide association signals of such miRNAs and genes could be non-independent because of local linkage disequilibrium. Enrichment analysis of association signals in...