Massimo Motta,Ettore Bennati,Elisabeth Cardillo,Laura Ferlito,Michela Passamonte,Mariano Malaguarnera.The significance of apolipoprotein-B (Apo-B) in the elderly as a predictive factor of cardio-cerebrovascular complications[J]. Archives of Gerontology and Geriatrics .2008(1)...
including unexpected mutations in apolipoprotein B (APOB). We aimed to determine the clinical significance of this non-oncogenetic mutation in HCC. An Apob gene signature was derived from genes that differed between control mice and
Apolipoprotein B mRNA-editing enzyme, catalytic polypeptides (APOBECs) are a class of cytosine deaminases with eleven primary family members: APOBEC1, Activation-Induced Deaminase (AID), APOBEC2, APOBEC3 (A–H), and APOBEC4. Alternative splicing of APOBEC3B, APOBEC3H, and APOBEC3F further di...
For example, inhibition of apolipoprotein C1 (APOC1) restores ferroptosis sensitivity, leading to the conversion of tumor-associated macrophages from an M2 to an M1 phenotype and enhancing anti-PDCD1 immunotherapy against hepatocellular carcinoma and lung cancers [280, 281]. Inhibiting PGE2-induced ...
After a median 48 months follow-up [19, (10 ~ 32) ], the levels of NGAL, sdLDL-C, hemoglobin A1c (HbA1c), LDL-C, and apolipoprotein B (ApoB) were significantly higher while those of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A I (ApoA–I) were lower in ...
Apolipoprotein E (APOE), a glycoprotein central to lipid transport and metabolism, has been implicated as a risk and/or protective factor in a wide range of illnesses. TheAPOEgene has three primary alleles, termed ɛ2, ɛ3 and ɛ4, with ɛ3 being the most common worldwide, but wit...
Intriguingly, we have shown here that the expression of Apolipoprotein CIII is down regulated more than 3 fold in plasma from breast cancer patients and about 1.5 fold in plasma from the carriers as compared to its level in the controls plasma. This provides another evidence for the potential ...
GPI, also known as apolipoprotein H, is a single-chain glycoprotein primarily produced in hepatocytes and present in plasma. It was first discovered by Schultzer in 1961. Recent studies have revealed that β2 glycoprotein 1 is the main antigen of antiphospholipid antibodies, and that it interacts...
of findings in murine atheroma to that observed in human cohorts. Ly6Chighmonocytes, the murine correlate of human classical monocytes, drive atherosclerosis in transgenic animal models based on the genetic deletion of apolipoprotein E or the LDL receptor [26,37,45,59-61]. Ly6Chighmonocytes ...
EH Corder AM Saunders WJ Strittmatter DE Schmechel PC Gaskell GW Small AD Roses JL Haines MA Pericak-Vance (1993)Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset familiesScience261921–92383464431:CAS:528:DyaK3sXmtVWjur8%3D ...