Apolipoprotein A-I and B concentrations were measured in 502 patients undergoing diagnostic cardiac catheterization to assess the predictive power of apolipoproteins B and A-I to discriminate between patients with coronary artery disease and those with normal coronary arteries as defined by coronary arter...
Apolipoprotein B synthesis inhibition by mipomersen reduces low-density lipoprotein cholesterol when added to maximally tolerated lipid-lowering medication in patients with severe heterozygous hypercholesterolemia. J Am Coll Cardiol. 2011;57(14):E492....
Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL particle number with outcomes in 25 clinical studies: assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices. Clin Chem. 2013;59(5):752-770. doi:10.1373/clinchem....
We also investigated the association between Apolipoprotein B/A1 ratio and the number of vascular lesions, using the Gensini scores and the Framingham risk score as related to severity of CHD. Furthermore, we assessed the potential of Apolipoprotein B/A1 ratio as a marker to predict ...
(B) Injection of immunopurified APOE aggregates from human AD brains (APOE3/3 and APOE4/4 patient-derived) into the prefrontal cortex of 2-month-old male 5xFAD mice. Tile scan images show the injection areas with MX04 (gray) and IBA1 (magenta) staining 2 months post-injection. Scale ...
Author information Author notes Summer F Acevedo & Brian J Piper Present address: *S.F.A. and B.J.P. contributed equally to this work. Current address (S.F.A.): Department of Physiology, Ponce School of Medicine, Puerto Rico 00732., Authors and Affiliations Departments of Behavioral Neu...
Clinically important apolipoproteins include apolipoprotein B-100, apolipoprotein B-48, apolipoprotein A-I, apolipoprotein C-II, apolipoprotein C-III, apolipoprotein E and apolipoprotein(a). Apolipoprotein B-100, apolipoprotein B-48 and apolipoprotein(a) form the structural backbone of atherogenic lipoprot...
Urinary ApoA-Ib can be detected using a specific antibody against the ApoA-I propeptide sequence. Plasma and urine samples of ApoA-Ib positive FSGS relapsing patients were resolved in 7-cm 2D SDS-PAGE gels using a 4–7 Ph range and stained with colloidal coomassie (panels A,B) or transferr...
<div p-id="p-0001">The invention provides a system for monitoring a patient that includes: 1) a blood test that measures an Apo E genotype or a derivative thereof from the patient to generate Apo B in
<div p-id="p-0001">The invention provides a system for monitoring a patient that includes: 1) a blood test that measures an Apo E genotype or a derivative thereof from the patient to generate Apo B in