The nuclear factor kappa B (NFκB) family of transcription factors is a key regulator of immune development, immune responses, inflammation, and cancer. The NFκB signaling system (defined by the interactions between NFκB dimers, IκB regulators, and IKK complexes) is responsive to a number ...
Crosstalk via the NF-κB signaling system 2008. Crosstalk via the NF-kappaB signaling system. Cytokine and Growth Factor Reviews 19:187-197.Basak S, Hoffmann A. Crosstalk via the NF-kappa B ... BA Hoffmann - 《Cytokine & Growth Factor Reviews》 被引量: 387发表: 2008年 Beyond IκBs: ...
Explore the NFkB pathway and its impact on inflammation and immune responses. Click here to learn more about this signaling pathway.
Vargas, A. Hoffmann Signaling via the NFkappaB system Wiley Interdiscip. Rev. Syst. Biol. Med., 8 (3) (2016), pp. 227-241, 10.1002/wsbm.1331 View in ScopusGoogle Scholar [33] F. Salamone, F. Galvano, F. Cappello, A. Mangiameli, I. Barbagallo, G. Li Volti Silibinin modulates ...
M-cell provides direct contact of immune cells in the intestinal lymphoid follicle to dietary antigens and microbiota via trans-epithelial transport and thus play a critical role in the mucosal immune response. However, the mechanisms that are involved in M-cell maintenance and its role in local...
NF-kappa BNeuronsSynapsesSynaptic Transmission行为, 动物NF-κB神经元突触突触传递Ca(2+)-regulated gene transcription is essential to diverse physiological processes, including the adaptive plasticity associated with learning. We found that basal synaptic input activates the NF-kappa B transcription factor ...
NF-κB is a transcription factor family that regulates the growth and survival of B cells; mantle cell lymphoma cells depend on NF-κB signaling for continued growth and proliferation. The NF-κB signaling pathways are categorized into canonical and non-canonical types, wherein the canonical pathwa...
NF-kappa B signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain... Fang, HuaLi, Hua-FengYang, MiaoLiao, RenWang, Ru-RongWang, Quan-YunZheng, Peng-ChengZhang, Fang-XiangZhang, Jian-Ping - 《Cell Cyc...
162 Hence, more studies are needed to explore the comprehensive role of IL-33 in psoriasis. Intracellular signaling pathways of transmission The NF-κB pathway One of the features of psoriasis is the elevated level of active, phosphorylated nuclear factor kappa B (NF-κB).128 NF-κB, a ...
Obesity is a complex, chronic disease and global public health challenge. Characterized by excessive fat accumulation in the body, obesity sharply increases the risk of several diseases, such as type 2 diabetes, cardiovascular disease, and nonalcoholic f