These biologic functions are also determinants in epithelial-mesenchymal transitions during embryonic development governed by the Snail family of transcription factors. Here we show that the activation of c-kit by SCF specifically induces the expression of Slug, a Snail family member. Slug mutant mice...
Western blot analysis of extracts from MO7e cells, untreated or stimulated with SCF #9907 (50 ng/ml for 2 minutes), using Phospho-c-Kit (Tyr719) Antibody (upper) or c-Kit Antibody #3392 (lower). 1/1 Learn more about how we get our images To Purchase # 3391 REQUEST A PRICE QUO...
c-Kit (Ab81) Mouse mAb detects endogenous levels of total c-Kit protein. It does not cross-react with other receptor tyrosine kinase family members. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant proteins containing the cytoplasmi...
Hair graying, an age-associated process of unknown etiology, is characterized by a reduced number and activity of hair follicle (HF) melanocytes. Stem cell factor (SCF) and its receptor c-kit are important for melanocyte survival during development, and mutations in these genes result in unpigme...
Gαi1 and Gαi3 were required for SCF-induced c-Kit internalization, as membrane c-Kit internalization was prevented by Gαi1/3 DKO in MEFs (Figure S2B). Total c-Kit protein levels were unchanged following SCF treatment in MEFs (Figure S2B)....
1007S TCF1 Blocking Peptide, 100 ug KIT Cell Signaling(CST) 1010S Acetyl- and Phospho-Histone H3 (Lys9/Ser10) Blocking Peptide, 100 ug KIT Cell Signaling(CST) 1011S Cleaved Caspase-8 (Asp391) Blocking Peptide, 100 ug KIT Cell Signaling(CST) 1013S Jak1 Blocking Peptide, 100 ug ...
For this purpose, we chose the pro-B cell line Ba/F3, which was retrovirally transduced with either splice form of c-Kit. Equal expression of c-Kit was verified by flow cytometry (Fig. 1). Cells were stimulated with SCF, followed by lysis and separation by SDS-PAGE and electrotransfer...
DGP rat model was established by single intraperitoneal injection of 2% streptozotocin and common diet. After successful modeling, the rats were treated once a day for 4 weeks. Positive ICC and SCF expressions were measured by immunohistochemistry. Results: Compared with group A, the gastrointestinal...
which are located in cryptopatches in the intestine. CCR6+ILC3s were attracted to the cryptopatches via the chemokine CCL20. Cryptopatch formation is altered in the absence of AHR or c-Kit-SCF signaling, which is controlled by AHR.68,136Within cryptopatches, CCR6+ILC3s interacted with myeloi...
Next, the slides were incubated in the dark with the reaction cocktail (EdU-Imaging kit, baseclick GmbH) as per manufacturer’s protocol for 30 min. Finally, slides were washed for 3 min in 3% BSA/PBS, followed by the immunofluorescence protocol. For β-Galactosidase staining, Senescence...