Sickle Cell Trait and Hemoglobin C Trait说明书
Hemoglobin C trait appeared to offer a slight protective advantage (p less than 0.1), but this did not reach statistical significance. These results do not disprove the malaria co-factor hypothesis in the etiology of 0urkitt's lymphoma, but deprive it of an additional indirect evidence in its...
N. M. Nseka心血管病(英文)Lepira FB, Mukendi TK, Mbutiwi FIN, Makulo JR, Sumaili EK, Kayembe PK, et al. Sickle cell trait, hemoglobin levels and anemia among black patients with predialysis chronic kidney disease: a post hoc analysis. World J Cardiovasc Dis. 2016;6:258....
Materials and Methods: Three groups were studied and consisted in 31 controls (group AA), 26 sickle cell trait (group AS) and 29 SCD patients (group SS) at steady state. Hemoglobin phenotype was assessed by combination of cation-exchange high performance chromatography (beta-thal short program ...
Synonym(s):sickle cell hemoglobin,haemoglobin S. Medical Dictionary for the Health Professions and Nursing © Farlex 2012 Hemoglobin S Hemoglobin produced in association with the sickle cell trait; the beta-globin molecules of hemoglobin S are defective. ...
If a child is born with one defective hemoglobin-beta gene, they may become acarrierof the disease. Carriers usually don’t develop SCD symptoms. But they can pass the disease on to their children if their partner also carries the sickle cell trait. ...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Interestingly, the sickle cell gene somewhat protects against malaria infection. This makes those with sickle cell trait (gene carriers) at least partially resistant to malaria. Furthermore, the geographic distribution of the sickle cell gene is similar to that of malaria infection. Sickle cell anemi...
(Stuart and Nagel, 2004). Individuals may carry thesickle cell traitwithout producing any symptoms.Sickle cell diseaseoccurs where HbS makes up more than 50% of the hemoglobin (Bolton-Maggs and Thomas, 2008). Hemoglobin S crystallizes causing the red blood cells to take on a “sickle” or ...
et al. Burden of sickle cell trait and disease in the Uganda Sickle Surveillance Study (US3): a cross-sectional study. Lancet Global Health 4, e195–e200 (2016). PubMed Google Scholar Serjeant, G. R. The natural history of sickle cell disease. Cold Spring Harb. Perspect. Med. 3, a...