Sickle Cell Anemia; Findings in Sickle Cell Anemia Reported from A.A. Abusham and Co-ResearchersAhmed Abusham
Fever is one of the principalreasons for the hospitalization of children afflicted by major sickle-celldisorder, since it can be a clinical reflection of severe infections that havethe potential to become life threatening. Objectives: Identification of the main causes offever in children with SCD ...
(1997) provide a comprehensive table of the expected skeletal changes in sickle cell, as distinguished from thalassemia or leukemia, cautioning that not all changes will occur in every case, and that the most characteristic features may not be evident before the age of 9 years. Sign in to ...
With the advent of improved therapy, an increasing proportion of individuals suffering from sickle cell disease (SCD) are surviving into adulthood. In contrast to children, little has been documented concerning the typical radiographic findings in adults presenting with sickle cell crises (SCC). We ...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Findings This cohort simulation modeling study showed that projected life expectancy (54 vs 76 years) and quality-adjusted life expectancy (33 vs 67 years) were lower in the sickle cell disease cohort relative to the non–sickle cell disease cohort. Projected lifetime income was also lower in ...
Ocular findings in homozygous sickle cell anemia in Jamaica###The progression of sickle cell eye disease in Jamaica###Unusual chorioretinal degeneration in sickle cell disease. Possible sequelae of posterior ciliary vessel occlusion###A randomized clinical trial of feeder vessel photocoagulation of proli...
Hemoglobin studies have been presented on a patient with clinically typical sickle cell anemia who was found to possess two major adult hemoglobins, Hb S and hybrid Hb GPhil./S. Four hemoglobins were demonstrated in his mother, Hb A, GPhil.,S and GPhil./S, in somewhat unexpected and as...
This helps red blood cells maintain their normal shape, which was expected to reduce hemolysis, restore red blood cell function and oxygen delivery to tissues, and ease the frequency and severity of VOCs.Who could take Oxbryta?Oxbryta was conditionally approved by the U.S. Food and Drug ...
Sickle cell anemia disease has been a great challenge to the world in the present situation. It occurs only due to the polymerization of sickle hemoglobin (HbS) having Pro–Val–Glu typed mutation, while the polymerization does not occur in normal hemogl