doi:10.1590/S1516-84842010000400002C. LoboAssociação Brasileira de Hematologia e HemoterapiaRevista Brasileira De Hematologia E HemoterapiaLobo C. Sickle cell disease--a serious problem for public health worldwide. Rev Bras Hematol Hemoter. 2010;32(4):280-1....
Visit the site to learn about sickle cell, a genetic disease. View patient stories, learn about the diagnosis, disease management, support resources, and more.
ImportanceSickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within capillary beds, resulting in sickle-shaped red blood cells, progressive multiorgan damage, and increased mortality. An estimated 300 000...
Since being recognized as a global public health concern by the United Nations in 2008, sickle cell disease (SCD) has remained a pressing health issue, particularly in low- and middle-income countries (LMICs).1 The annual commemoration of World Sickle Cell Day on June 19 has drawn attent...
access to treatment, and an enhancement of the quality of life for those affectedby it.Sickle Cell Disease (SCD) is the most prevalent severe monogenic disorder globally. India represents 14.5% of all newborns with SCD worldwide, totalling more than 42,000 each year, second only...
Sickle cell disease is caused by inherited mutations in the beta-globin gene, leading to sickle-shaped red blood cells that are rigid and prone to getting trapped in small vessels, slowing or stopping the flow of blood. This can cause severe pain, anemia and organ damage. ...
malaria. About 8%-10% of African Americans carry a single gene for sickle cell disease (sickle cell trait), but more than 100 million people worldwide have the trait, including people of African, Central and South American, southern European (Mediterranean), South Asian, and Middle Eastern ...
CSL We Are CSL Vita: Original Stories 2018 The Impact of Sickle Cell Disease The Impact of Sickle Cell DiseaseWhy CSL Behring is exploring new treatment options for this rare disease. By Greg Healy 29 Oct 2018 Topics Wellness This is a modal window. The Playback API request failed for an...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Sickle cell disease is an autosomal recessive blood disorder that can lead to anaemia. It is caused by a mutation in the haemoglobin gene, which leads to deformation of red blood cells. Deformed red blood cells can obstruct small vessels and they are prone to destruction. ...