As a busy mom and freelance makeup artist and hair stylist, Lesly has a lot on her plate. Managing her sickle cell disease - and all the challenges it brings - doesn't make her day-to-day any easier. Yet Lesly is determined to be there for her kids and her clients, while also spe...
ImportanceSickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within capillary beds, resulting in sickle-shaped red blood cells, progressive multiorgan damage, and increased mortality. An estimated 300 000...
ImportanceSickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within capillary beds, resulting in sickle-shaped red blood cells, progressive multiorgan damage, and increased mortality. An estimated 300 000...
ABSTRACT: Sickle cell disease is the most common inherited blood disorder, affecting millions of people worldwide. Although sickle cell disease can be found in various areas of the world, it predominantly affects individuals of African or Hispanic heritage. The hallmark clinical symptoms are due ...
The trait is strikingly common—about one in 13 African American babies has sickle cell trait, according to the Centers for Disease Control and Prevention (CDC). About 100 million people have sickle cell trait worldwide, according to the American Society of Hematology. ...
Acute chest syndrome (ACS) is a leading cause of death from sickle cell disease worldwide accounting for about 25% of all deaths. The aim of this study was to determine the prevalence, clinical features and outcome in Port Harcourt, Nigeria. Materials and Methods: A retrospective cohort study...
Two groundbreaking cell-based gene therapies, exagamglogene autotemcel and lovotibeglogene autotemcel, were recently approved by the FDA for the treatment of sickle cell disease.
Sickle cell disease (SCD) is the most common hematologic inherited disorder worldwide and a public health priority1. The majority of the world’s SCD burden is in sub-Saharan Africa, affecting millions of people at all ages. It is estimated that 200,000–300,000 children are born with SCD...
ImportanceSickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within capillary beds, resulting in sickle-shaped red blood cells, progressive multiorgan damage, and increased mortality. An estimated 300 000...
Sickle Cell Disease ImportanceSickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within capillary beds, resulting in sickle-shaped red blood cells, progressive multiorgan damage, and increased mortality. An...