Obaro, S. ( 2009 ) Pneumococcal infections and sickle cell disease in Africa: does absence of evidence imply evidence of absence? Archives of Disease in Childhood , 94 , 713 – 716 .Obaro S. Pneumococcal infections and sickle cell disease in Africa: does absence of evidence imply evidence ...
Sickle cell disease is a genetic condition that people are born with, so there isn't a way to prevent it. By law, all babies born in the U.S. are screened for sickle cell at birth. A child must inherit a sickle cell gene from both parents to develop the disease. Genetic testing al...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Children with sickle cell disease are also vulnerable to infections (especially those caused by Pneumococcus organisms), organ damage related to episodes of ischemia, and, in some cases, early death.95 Sickle cell disease is most prevalent among African-Americans and Hispanic-Americans; approximately ...
Sickle-Cell DiseaseFeverMalariaAcute Lower Respiratory Infections (ALRIGabonSickle-cell disease (SCD) represents asubstantial public health problem in Gabon. Fever is one of the principalreasons for the hospitalization of children afflicted by major sickle-celldisorder, since it can be a clinical ...
Sickle cell disease or sickle cell anemia is the most common of the hereditary blood disorders among black people of African descent worldwide. Learn about symptoms, treatment, causes, inheritance, testing, complications, and more.
Sickle cell disease (SCD) is a group of inherited conditions affecting the protein inside our red blood cells that helps deliver oxygen throughout the body. This protein is called hemoglobin. Individuals with SCD have a variant that changes the shape of
Bacterial infections are considered a major cause of morbidity and mortality in patients, particularly children, with sickle cell disease. Infections including pneumonia, meningitis, osteomyelitis, pyelonephritis and general sepsis are more prevalent in patients with these genetic abnormalities than in normal...
Sickle cell disease (SCD) is a serious genetic disease. The condition is present throughout a person’s entire life and gets progressively worse over time. While most people associate SCD with frequent episodes of excruciating pain, people living with this disease also face an increased risk of...
PRIMER Sickle cell disease Gregory J. Kato1, Frédéric B. Piel2, Clarice D. Reid3, Marilyn H. Gaston4, Kwaku Ohene‑Frempong5, Lakshmanan Krishnamurti6, Wally R. Smith7, Julie A. Panepinto8, David J. Weatherall9, Fernando F. Costa10 and Elliott P. Vichin...