Sickle cell disease is a common and life-threatening haematological disorder that affects millions of people worldwide. Abnormal sickle-shaped erythrocytes disrupt blood flow in small vessels, and this vaso-occlusion leads to distal tissue ischaemia and inflammation, with symptoms defining the acute ...
Sickle-cell disease affects 8 million people globally4, particularly in resource-limited regions where the intricacies of transplants may pose a barrier to treatment. So, the need to ensure the accessibility of novel treatments is paramount. The emerging focus on disease-modifying therapies (DMTs),...
Sickle cell disease is a genetic blood disorder that can lead toanemia, body pain and organ damage. This disease affects hemoglobin, a protein in red blood cells that carries oxygen through the body. Without getting the right amount of oxygen, your child’s tissues and organs could be damaged...
SCD also affects people from Hispanic, southern European, Middle Eastern, and Asian Indian backgrounds. Types of Sickle Cell Disease There are several forms of sickle cell disease. The type you or your child inherits depends on many things, including the specific type of abnormal hemoglobin you ...
SICKLE CELL DISEASE Sickle cell disease is a genetic hematological disorder that affects the hemoglobin in red blood cells, causing the hemoglobin to form crystalloids that become less elastic than normal hemoglobin, resulting in long, misshapen red blood cells that have a “sickled” appearance. The...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
When you have sickle cell disease, you deal with pain. At UVA, you’ll have a dedicated team with a personalized plan to keep you healthy and active.
Sickle cell disease or sickle cell anemia is the most common of the hereditary blood disorders among black people of African descent worldwide. Learn about symptoms, treatment, causes, inheritance, testing, complications, and more.
Sickle cell disease is an inherited disease that affects the shape of the red blood cells. The disease causes the red blood cell to adapt a sickle like shape. This can cause issues because it does not flow through the body's vessels th...
Sickle cell disease (SCD), a blood disorder that primarily affects people of African ancestry, can cause a variety of symptoms in patients, including stroke and cognitive impairment. Hyacinth I. Hyacinth, Ph.D., MBBS, studies racial health disparities in neurological conditions at the University o...