Advances in pediatric sickle cell care Review between ages 5 mo and 2 y represent most cases of splenic sequestration (31). During severe sequestration crisis, the blood-filled spleen may enlarge to the point of filling the entire abdomen, the hemoglobin may drop acutely (at least 2 g/dl...
Osunkwo I, Andemariam B, Minniti CP, Inusa BPD, El Rassi F, Francis-Gibson B, et al. Impact of sickle cell disease on patientsʼ daily lives, symptoms reported, and disease management strategies: results from the international sickle cell world assessment survey (SWAY). Am J Hematol. ...
of acute vasoocclusive sickle cell crisis. Am J Hematol Patterns of arginine and nitric oxide in patients with 2000;64:15—9. sickle cell disease with vaso-occlusive crisis and acute [15] Aquino SL, Gamsu G, Fahy JV, et al. Chronic pulmonary chest syndrome. J Pediatr Hematol Oncol 2000;...
Blood selected for transfusion for patients with sickle cell anaemia should meet the criteria listed intable XI. Because the majority of patients with sickle cell anaemia are Africans or African-Americans and because they receive blood given by Caucasians, there is a high incidence of allo-immunisat...
The primary outcome, visit to a medical facility, was one of the criteria to define occurrence of painful crisis. Cost estimates were applied to all outpatient and emergency department visits and inpatient hospital stays that were classified as a crisis. Other resources for which cost estimates ...
The diagnosis of sickle cell nephropathy is made by detecting abnormalities such as albuminuria, hematuria or CKD rather than by distinct diagnostic criteria in SCD, which have not been developed. Traditional markers of kidney function such as serum creatinine and eGFR should be interpreted with cauti...
MAIN RESULTS: Of the 47 studies identified, two met the inclusion criteria. The first study tested the effectiveness of zinc sulphate to prevent sickle cell-related crises in a total of 145 participants and showed a significant reduction in painful crises over one and a half years, mean ...
Study participants were children with sickle cell disease, 5 to 19 years of age, who were experiencing pain. Children were selected from the Hematology/Oncology Unit at Children's Hospital Oakland based on the following criteria: 1) admission of the child to the inpatient unit for a vaso-occlu...
Role of child and maternal processes in the psychological adjustment of children with sickle cell disease. In this study, 64% of children aged 7-12 years with sickle cell disease were found to have a parent-reported behavior problem, and 50% met the criteria for... RJ Thompson,KM Gil,DJ...
Once a fatal disease of childhood, more than 95% of patients born today with sickle cell disease (SCD) in developed countries are expected to survive into adulthood, largely because of improvements in supportive and preventive care (newborn screening, pe