Sickle cell disease refers to a group of disorders resulting from mutations in the hemoglobin gene that can lead to deformation of the red blood cell (RBC) into a crescent, or sickle, shape. From: Pediatric Emergency Medicine, 2008 About this pageAdd to MendeleySet alert ...
Peripheral blood smear showing a mixture of RBCs, some with round normal morphology and some with sickling (elongation and bending) Image:“Sickle Cell Anemia” by Ed Uthman. License: CC BY 2.0 Related videos 3:58 Sickle Cell Anemia: Clinical Pathology and Diagnosis 1:25 Sickle Cell Anemia:...
a woman is found to be a carrier for sickle cell, testing should be offered to her partner. Sickle cell tests may also be ordered when a person has abnormal results on acomplete blood count (CBC)andblood smearand/or has signs and symptoms that suggest the presence of sickle cell anemia....
Sickle cell disease or sickle cell anemia is the most common of the hereditary blood disorders among black people of African descent worldwide. Learn about symptoms, treatment, causes, inheritance, testing, complications, and more.
However, there are also some drawbacks to using a blood smear to diagnose sickle cell disease, which our automated system is unable to overcome. One of these is that using blood smear slides to diagnose sickle cell disease or sickle cell anemia is not effective for infants and can cause ...
Correction of sickle cell disease by homologous recombination in embryonic stem cells. Blood 108, 1183–1188 (2006). Article CAS PubMed PubMed Central Google Scholar Leonard, A., Tisdale, J. & Abraham, A. Curative options for sickle cell disease: haploidentical stem cell transplantation or ...
It is possible to cure this disease easily,if it can be detected at an earlier stage before severe complications occurs. In the present paper we have designed a real time system for the diagnosis of sickle cell anaemia from blood smear images.Parvathy B.HHariharan SAruna N.S...
Sickle cells in peripheral blood smear are usually seen in sickle cell disease. However in certain very rare conditions, pseudosickle cells may be seen. The present study reports two cases of iron deficiency anemia with presence of pseudo sickle cells in the peripheral blood films which lead to...
Only thosefiles that contained at least the following five fundamental medicalexaminations were retained for further evaluation: Complete Blood Count (CBC),blood smear, blood culture, urine culture and chest X-ray. Out of a total of118 admissions (103 patients), 87 (73.7%) were due to the ...
Sickle cell disease (SCD) was first described in 1910 in a dental student from the West Indies presenting with recurrent painful episodes, hemolytic anemia, and jaundice (1). On microscopic review of the patient’s blood smear, Dr. James Herrick and his intern, Dr. Ernest Irons, identified ...