Sickle cell anemia.Investigates sickle cell anemia, a genetic hemoglobinopathy. Patients at risk of sickle cell anemia; Assessment findings; Genetic screening and counseling as primary forms of prevention; Treatment in acute cases; Pathological effect of the disease; Patient teaching points.Mitchell...
The hematological and clinical data in 97 sickle-cell anemia cases and hematological findings of their parents are reported. In spite of the low Hb values of the patients, they tolerated their anemia and very rarely required blood transfusions. The Hb F levels of the patients were in general ...
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Sickle cell anemia disease has been a great challenge to the world in the present situation. It occurs only due to the polymerization of sickle hemoglobin (HbS) having Pro–Val–Glu typed mutation, while the polymerization does not occur in normal hemoglobin (HbA) having Pro–Glu–Glu peptides...
Cardiovascular findings are described in seven children with sickle cell anemia. Clinically the following features were noted: (1) exertional dyspnea and fatigue; (2) wide fixed splitting of the second heart sound; (3) third "filling" heart sound in five of the seven cases; (4) systolic mur...
Ocular findings in homozygous sickle cell anemia in Jamaica###A study of macular pigmentation in human eyes. Título: Ocular findings in homozygous sickle cell anemia in Jamaica Fonte: Am J Ophthalmol;73(4):533-43, Apr. 1972. Idioma: En. Resumo: Retinal... PI Condon 被引量: 0发表: 0...
Investigated the psychological adjustment of children with sickle cell anemia (SCA) and their healthy siblings during a noncrisis period. 13 SCA children, aged 8–17 yrs, along with their healthy siblings, matched for sex and age, and maternal caretakers completed self-report measures assessing aff...
Sickle Cell Anemia Sickle cell is a homogenous genetic anemia caused when an abnormal gene (hemoglobin S or HbS) causes the substitution of the amino acid valine, for another, glutamic acid (Amundsen et al., 1984). The sickle gene protects heterogeneous carriers (HbC) from P. falciparum in ...
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Assessment of perioperative transfusion therapy and complications in sickle cell disease patients undergoing surgery. A. Pasha, “Assessment of Perioperative Transfusion Therapy and Complications in Sickle Cell Disease Patients Undergoing Surgery,” Middle East Journal of Anesthesiology, Vol. 19, No. 5, ...