Subirana, J.A. & Messeguer, X. The most frequent short sequences in non-coding DNA. Nucleic Acid Res. 38, 1172-1181 (2009).The most frequent short sequences in non-coding DNA. Subirana Juan A,Messeguer Xavier. Nucleic Acids Research . 2009...
The rates of evolution of purified long and short repetitive \{DNA\} sequences were examined by hybridisation analysis between the \{DNAs\} from several species of sea urchins. We find that the rates of nucleotide substitution are very comparable within mutually retained sequences for the two ...
Novel DNA sequencing technologies with the potential for up to three orders magnitude more sequence throughput than conventional Sanger sequencing are emerging. The instrument now available from Solexa Ltd, produces millions of short DNA sequences of 25 nt each. Due to ubiquitous repeats in large gen...
A、genetic engineering B、biotechnology C、recombinant DNA D、gel electrophoresis E、gene probes 暂无答案
An in-depth analysis of the flanking sequences around the breakpoints (See Methods) showed that novel adjacencies are often associated with small losses or gains of genetic material indicating imperfect fusion of chromosomal fragments (Supplementary Fig. 5). Additionally, we searched for microhomology...
Another dimension of advancement has been the emergence of long-read sequencing platforms that can sequence longer individual DNA molecules. These so-called “third generation” platforms, such as PacBio and Oxford Nanopore long read technologies, have evolved to a cost per acquired base that now ...
The alignment of short DNA read sequencing data to a human reference genome sequence has become a standard step in the analysis pipeline for short DNA read sequence data. As the rate at which short read DNA sequence data is being produced doubles every 5 months, analysis of this data in a...
We have carried out the molecular characterization of a highly repeated DNA element, called E12 , from Trypanosoma cruzi , which has been found to be interspersed along its genome. The E 12 element, repeated about 5.6 × 10 3 times, is found in most of the chromosomal bands of the parasit...
Sequence, structure and functional diversity of PD-(D/E)XK phosphodiesterase superfamily. Nucleic Acids Res. 40, 7016–7045 (2012). Article CAS PubMed PubMed Central Google Scholar Buisson, M. et al. A bridge crosses the active-site canyon of the Epstein–Barr virus nuclease with DNase ...
A microsatellite is a short tandem repeat sequence with 10–50 repetitions of a small DNA motif, found throughout the genome. From:Biomedicine & Pharmacotherapy,2022 About this page Set alert Chapters and Articles You might find these chapters and articles relevant to this topic. ...