Microtubule organization is determined by the shape of epithelial cellsInterphase microtubule organization is critical for cell function and tissue architecture. In general, physical mechanisms are sufficient to drive microtubule organization in single cells, whereas cells within tissues are thought to ...
The team of researchers behind the discovery set to tackle this very problem. Parts of this twisting problem have been answered, but scutoids provided another unique piece. The team used, worked with and discovered this shape in the most flexible cells in nature—epithelial cells. Different Kinds...
For example, in murine small intestinalorganoids, the cellular aspect ratio is found to be a keyphysical parameterfor patterning epithelial cell progeny [36]. Moreover, micropatterning of single cells to manipulate their shapes revealed that cell geometry influences stem cell differentiation by ...
- 《Cell & Tissue Research》 被引量: 90发表: 1999年 Proliferation and differentiation of midgut epithelial cells from Manduca sexta, in vitro We have developed an insect midgut primary cell culture from pharate fourth instar larvae of Manduca sexta. An enriched Grace''s medium supplemented with...
Tissue morphogenesis requires the coordinated regulation of cellular behavior, which includes the orientation of cell division that defines the position of daughter cells in the tissue. Cell division orientation is instructed by biochemical and mechanical signals from the local tissue environment, but how...
Actomyosin-mediated contractility is a highly conserved mechanism for generating mechanical stress in animal cells and underlies muscle contraction, cell migration, cell division and tissue morphogenesis. Whereas actomyosin-mediated contractility in striated muscle is well understood, the regulation of such ...
Explain the structure and function of the cell membrane. How are epithelial cells adapted to their function? What is the role of the nucleus in cell division? What are the structural features of a microglial cell? What is the function of neuroglial cells in nervous tissue?
The EGF receptor is one of many receptors that aid in cell growth regulation. It is found on most types of mammalian epithelial cells, which line body surfaces and organs, and can respond to several types of growth factors in addition to EGF. Some types of cancer, especially lung cancer an...
Here, we develop a minimal continuum model of a planar epithelial tissue as an active elastic material that incorporates all these features. We start from a full three-dimensional (3D)description of the tissue and derive an effective 2D model that captures, through the curvature of the apical ...
Crystals with large active faces have a large contact area with epithelial cell surface, and crystals with sharp edges can easily scratch epithelial cells; these factors could promote crystal adhesion and aggregation, thus increasing stone risk....