Understanding the genetics of brain structure and mental health susceptibility can help us better prevent, diagnose and treat these conditions. The concept of the "human brain" first appeared inancient Greece around 335 BCE. The philosopher Aristotle described it as a radiator that prevented the hear...
There were already indications of a genetic link between the shape of our face and that of our brain, says Professor Peter Claes from the Laboratory for Imaging Genetics at KU Leuven, who is the joint senior author of the study with Professor Joanna Wysocka from the Stanford University School ...
Zoom Summary:A new study uncovered how epigenetic marks and the Cux2 protein influence brain folding. The study reveals that the epigenetic mark H3K27ac and Cux2 are key to forming the cerebral cortex’s gyri and sulci. These findings enhance our understanding of brain development and could ...
Evidence from model organisms and clinical genetics suggests coordination between the developing brain and face, but the role of this link in common genetic variation remains unknown. We performed a multivariate genome-wide association study of cortical surface morphology in 19,644 individuals of Europea...
Genetics This article is cited by Phylogeography and population structure of Ponticola gorlap (Teleostei: Gobiidae) in an evolutionary distinctive and ecologically threatened Caspian Sea sub-basin Fatah Zarei Hamid Reza Esmaeili Ali Gholamhosseini ...
The retinotectal projection has long served as an experimentally accessible model for the study of topographic map formation and function. Retinal ganglion cells (RGCs) project to their midbrain target, the optic tectum, such that neighbor relationships are preserved...
Recent studies in both cell culture and developing embryos have combined live imaging, computational analysis, genetics, and biophysics to identify ratchet-like behaviors in actomyosin networks that operate to incrementally change cell shape, drive cell movement, and deform tissues. Our analysis of ...
Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), were cultured from newborn rat brain and optic nerve to study how they differentiate in vitro in the absence of neurons. By use of galactocerebroside (GC) as a reference marker, the development of the cell phenoty...
"It is surprising and somewhat disappointing that we still don't know what makes the human brain different from the brains of other closelyrelated species," said Nenad Sestan, the Harvey and Kate Cushing Professor of Neuroscience at Yale, professor of comparative medicine, of genetics and of psy...
The properties of the image-forming elements of the human eye are compared with the properties of the retina-brain system by considering them as two linear... FW Campbell - 《Proceedings of the IEEE》 被引量: 115发表: 1968年 Depth of Focus of the Human Eye * The properties of the image...