Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the ...
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. Dig Dis Sci. 2011;56(11): 3195 -3203.Meng Y, Wang QG, Wang JX, Zhu ST, Jiao Y, et al. (2011) Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma . Dig Dis Sci 56 : 3195–...
中图分类号密级雄激素非依赖性前列腺癌PC.3细胞中SFRP.1基因甲基化情况及三氧化二砷去甲基化的研究ArsenictrioxideandSFI冲一1genemethylationinandrogen—independentPC一3prostatecancercells计:学位论文:38页表格:5个插图:6幅郑磊指导教师:**教授申请学位级别:硕士学位学科(专业):外科学培养单位:大连医科大学附属第一医...
结直肠癌患者血清SFRP1基因甲基化的检测及临床意义
关键词:sFRPl ;启动子;荧光素酶报告基因载体;H cv核心蛋白中图分类号:R 373.21;R 394.3文献标志码:AH CV Coreprotei ni nhi bi ts SFRPlgene prom oter acti Vi tyQ U AN H ui - qi n,N IE D an,zH O u Fan,CH EN Li n—l i n,CH ENQ i ng-m ei ,SH ANXi ao—l i ang,XIE Q ...
质控品 阳性质控品 CBPE0393 SFRP1 Methylation Positive control 1ug 99.88% 阴性质控品 CBPE0394 SFRP1 Methylation Negative control (< Cut off) 1ug 0.00% 参考品 强阳性参考品-1 CBPE0395 SFRP1 Methylation Reference Standard with > 85% ...
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Huh7 , SFRP1 (-407～-27bp,-837～-27bp,-1202～-27bp,-1619 ～-27bp,-2029～-27bp), pGL3 Basic SFRP1 。 pRL TK HEK293 , ; HCV GFP SK Hep1 , AdCore SFRP1 。 SFRP1 -407～-27bp ; pGL3 Basic , 37 31±4 45 (P< 0 01),pGL3-S2～S5 28 74±2 47、13 56±2 52、12 97...
【标准品】Mutation 【标准品】Fusion 【标准品】Translocation 【标准品】CNV 【标准品】Panel 【标准品】TMB 【标准品】DdPCR探针引物 【标准品】病毒 【标准品】用药指导 【标准品】地中海贫血 【标准品】MSI 【标准品】遗传性耳聋 【标准品】MRD dPCR检测试剂盒 【标准品】NIPT 【标准品】SMA-SMN1/2 【...
Objective To investigate the effects of HCV Core on SFRP1 gene promoter activity. Methods Different lengths of the 5'-flanking region of SFRP1 promoter were amplified from hepatoma cell line Huh7 genome DNA by PCR methods. The products were cloned into pGL3-Basic vector. The recombinant reporter...