While changes in alternative splicing patterns play an integral role in normal development and cell differentiation, numerous cancer-specific aberrant splicing patterns have been documented6,7. However, it is currently unclear whether the observed splicing abnormalities are a by-product of cellular ...
The GNAQ, GNA11 and NRAS genes are now thought to play a role in the initiation of tumorigenesis, while mutation in SF3B1 (or BAP1) would then occur in a later phase of the oncogenic process [18]. The co- occurrence of an NRAS and an SF3B1 mutation in the CNS melanoma of the ...
plus new pros - Skate to songs from the era-defining soundtrack along with new music - Hit insane trick combos with the iconic handling of the Tony Hawk’s™ Pro Skater™ series - Play all the original game modes and go head-to-head with local 2-Player modes - Show off your style...