We now extend these findings to include potential sex-dependent dopaminergic system dysfunctions at a very early stage of the disease (i.e. 8 weeks of age). In this present study, we show that female (but not male) HD animals were less responsive to the effect of the dopamine–...
9 OT+ PVN neurons innervate dopaminergic circuitry in a sexually dimorphic manner. a,b, Quantification of OT+ PVN anterograde projections to various brain regions of wild-BX mice following the semi-natural experiment: representative images of non-dopaminergic regions showing OT+ PVN fibers (white; ...
Prolactin (PRL) is a pleiotropic hormone that was identified in the context of maternal care and whose release from the anterior pituitary is primarily controlled by Neuroendocrine Dopaminergic (NEDA) neurons of the Arcuate Nucleus of the Hypothalamus. The sexually dimorphic nature of PRL physiology ...
R. Caenorhabditis elegans male sensory-motor neurons and dopaminergic support cells couple ejaculation and post-ejaculatory behaviors. eLife 3, e02938 (2014) Article Google Scholar Oren-Suissa, M., Bayer, E. A. & Hobert, O. Sex-specific pruning of neuronal synapses in Caenorhabditis elegans. ...
GABA interneurons. Copulation persistence ensures the maintenance of copulation before sperm transfer in the presence of stressful stimulus and is regulated by opposing actions of 8dsx/GABA and the dopaminergic system in the ventral cord24. This persistence requires optimal sensory input from the ...
(female STS) Differentially expressed in male vs female frontal lobe regions during normal neurodevelopment [14]; neuronal differentiation, and specifically promotes the generation of neurons of dopaminergic fate and possibly other types of neurons [63] This suggests that these miRNAs may be involved ...
complex gender-specific social, emotional, and cognitive functions may rest upon the coordination of OXT and CRH actions by CRHBP expression in OxtrINs or other cellular and molecular mechanisms that are fine-tuned to modulate local, higher order circuitry in response to remote sexually dimorphic ...
**p < 0.01; ***p < 0.001 13 X‑linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of… 7049 its sexually dimorphic expression determined by the sex chromosome complement (XX > XY), we decided to focus our study henceforth on its involvement in ...
GABA interneurons. Copulation persistence ensures the maintenance of copulation before sperm transfer in the presence of stressful stimulus and is regulated by opposing actions of 8dsx/GABA and the dopaminergic system in the ventral cord24. This persistence requires optimal sensory input from the ...
For the purpose of this review, a sexually dimorphic response is considered a phenotypic effect that either differs in absolute occurrence between the sexes (with a response present in one sex but absent in the other) or a significant difference in the magnitude of the intensity. For instance,...