必应词典为您提供sex-hormone-binding-globulin的释义,un. 性激素结合球蛋白; 网络释义: 性荷尔蒙结合球蛋白;性贺尔蒙结合球蛋白;性荷尔蒙捆绑球蛋白;
SHBG（性激素结合球蛋白）是一种重要的蛋白质，在体内具有调控性激素生物活性的重要作用。SHBG主要由肝脏合成，其主要功能是将性激素如雄激素和雌激素结合并在体内循环，从而调节这些性激素的生物活性，影响性激素的代谢和分布。目录号 PA1000-8935 在研究性激素相关疾病和药物开发过程中，重组SHBG蛋白被广泛应用。重...
Androgen binding activity, indistinguishable from sex-hormone-binding globulin (SHBG) in serum, has been identified in human follicular fluid by binding analyses (saturation and Scatchard analyses and binding specificity), immunoradiometric assay and Con-A Sepharose chromatography. Follicular fluid was obta...
Human sex hormone-binding globulin (SHBG) regulates the cellular bioavailability of SHBG-bound steroid hormones. Subtle decreases in plasma SHBG levels during puberty have a perceptible effect on the androgen-estrogen balance. This SHBG decrease is more pronounced in girls with premature pubarche who ...
Sex hormone-binding globulin (SHBG) levels in serum are affected by thyroid status; hyperthyroidism is associated with high SHBG levels, whereas hypothyroid patients have low or normal SHBG levels. This study was undertaken to test the usefulness of SHBG determinations to define the thyroid status ...
OBJECTIVE: A relationship between hyperinsulinemia and decreased serum sex hormone-binding globulin (SHBG) has been described in adults. We evaluated the usefulness of SHBG as an index of hyperinsulinemia and/or insulin resistance in obese children (aged 6-9 years) of both sexes and its possible ...
Exogenous hormones are used by more than a hundred million women worldwide as oral contraceptives or for postmenopausal hormone replacement. Oral contracep... FR Rosendaal,FM Helmerhorst,JP Vandenbroucke - 《Arteriosclerosis Thrombosis & Vascular Biology》 被引量: 890发表: 2002年 A Reduced Sensitivi...
Sex hormone-binding globulin (SHBG) is the high-affinity binding protein for androgens and estrogens. According to the free hormone hypothesis, SHBG modulates the bioactivity of sex steroids by limiting their diffusion into target tissues. Still, thein vivophysiological role of circulating SHBG remains...
Aims: The aim of this study was to evaluate the predictive value of sex-hormone-binding globulin (SHBG) for the diagnosis of gestational diabetes mellitus (GDM), and to clarify the association between SHBG levels and GDM complications/medication requirements. Material and Methods: Among the partici...
Total testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation, in comparison with the omnivores, the vegans...