COMPOSITION FOR SEPARATING SERUM OR PLASMAPROBLEM TO BE SOLVED: To suppress the extent of flow or phase separation significantly even after long time preservation by adding dicyclopentadien resin and silica hav
discovery[124–128]. Plasma and serum are two distinct matrices; plasma is the liquid that remains when clotting is arrested with the introduction of ananticoagulant, while serum is obtained after blood has clotted. Thus, theirlipid profilesdiffer even when obtained from the same blood draw [129...
Plasma:bloodobtainedfromabloodvesselthathasbeentreatedwithanticoagulation,obtainedbycentrifugation,withoutthecellcomposition,thatis,theplasma. Serum:thefluidreleasedfromabloodclotafterclottingofthebloodinvitro,i.e.,serum. Roughlyspeaking,thedifferencebetweenserumandplasmamainlyliesinserumwithoutfibrin. ...
The importance of the intestinal flora, which repre- sent a strong antigenic stimulus for the whole orga- nism, has been confirmed by many experimental stud- ies. It influences the development of immune reactions and preforms them, to some extent, for the rest of life [35]. In a study ...
We describe a robust nano liquid chromatography-mass spectrometry (nanoLC-MS) platform for measuring the total amount of OT in human plasma/serum. OT binds strongly to plasma proteins, but a reduction/alkylation (R/A) procedure breaks this bond, enabling ample detection of total OT. The ...
Our results further show that modulations in the microbial composition of the gut result in heightened serum IgA concentrations that coincide with colonization of the BM by large numbers of IgA-secreting plasma cells and marked changes in the serum IgA repertoire. Such antibodies are induced by a ...
SHBG production occurs in the liver and is influenced by insulin sensitivity and body fat composition during pregnancy [36, 52, 55]. Although SHBG’s main function is to bind sex steroids to reduce free sex hormone levels, SHBG has also been found to link inversely to insulin resistance ...
In agricultural animal studies, the association of serum and plasma metabolites with disease [18], meat quality traits [19], feed intake [20] and growth traits [21] has been reported. Serum and plasma are now commonly used as biological samples in metabolomic studies because of their easy ...
Profiling of the serum/plasma is also of interest as it may contain potential diagnostic and prognostic biomarkers. The identification of reliable serum response markers to evaluate the effects of drug therapy would potentially lead to accurate clinical decisions and better outcome for patients [10,11...
An online atlas of human plasma metabolite signatures of gut microbiome composition Article Open access 23 September 2022 Introduction The gut microbiome has recently been shown to play an important role in cardiovascular disease (CVD) and various other disorders1,2,3. Especially the gut metabolite...