Here we hypothesized distinct molecular circuits of microRNA/LD-associated target genes and searched for mechanistically linked serum and tissue biomarkers that would distinguish between DIS and human NAFLD of different grades. We analysed >800 rat hepatic whole genome data for 17 steatotic drugs and...
Therefore, the objective of this study was to evaluate plasma cortisol differences between a stressful (manual restraint) and painful (castration) event under controlled conditions. One hundred cross-bred male pigs 9 to 11 d of age were chosen at random from 24 litters. Fifty piglets were ...
DCE-MRI-based Peak Enhancement Intensity (PEI), Time to PEI (TPEI) and their maximum intensity time ratio (MITR: PEI/TPEI) values were significantly different between the different monoclonal plasma cell disease stages, PEI values increasing and TPEI values decreasing progressively along the ...
Distinguish between an antigen and an antibody. Distinguish between meningitis and encephalitis conditions by causative microbes. Differentiate between the serological tests used to identify isolated cultures of pathogens and those used to diagnose disease from the patient's serum...
The biological data can be from health data, clinical data, or from a biological sample, (e.g., a biological sample from a human, e.g., serum, blood, saliva, plasma, nipple aspirants, synovial fluids, cerebrospinal fluids, sweat, urine, fecal matter, tears, bronchial lavage, swabbings,...
GADD45a methylation in serum DNA was examined in 82 patients (34 cancer and 48 benign). Results: There was no significant difference in buffy coat GADD45a methylation between cancer and benign patients. Serum GADD45a methylation was significantly higher in cancer than in benign patients. ...
Serum samples from these patients were collected once between the first to third days of their hospitalization. Permission to conduct the study was given by the Ethics Committee of the National Center for Global Health and Medicine, and written, informed consent was obtained from all patients (NC...
Mice fed a HFHC diet developed steatohepatitis and had higher body weight and liver weight; higher hepatic triglyceride, diglyceride, cholesterol ester, and free cholesterol concentration; higher plasma ALT, cholesterol, and insulin levels; and lower serum adiponectin levels than mice fed a HF diet ...
plasma B-type natriuretic peptide (BNP) levels in subjects. All subjects were assessed for serum creatine kinase isoenzyme-MB (CK-MB), cardiac troponin I (cTnI), and myoglobin (MYO) after admission. We investigated the effectiveness of BNP and other cardiac biomarkers in the diagnosis of ...
We were the first to show, using serum 1H NMR metabolomics, that RRMS and SPMS can be differentiated13 and highlighted the potential of this technique to objectively distinguish between these two phases of MS. Other studies have since followed suit, further validating the presence of distinct ...