(1992). Naltrexone, serotonin receptor subtype antagonists, and glucoprivic intake: 1. 2-Deoxy-D-glucose. Pharmacol. Biochem. Behav., Aug; 42(4): 661-70ISLAM A., ET AL.: " Naltrexone, Serotonin Receptor Subtype Antagonists, and Carbohydrate Intake in Rats " PHARMACOLOGY BIOCHEMISTRY AND ...
The serotonin receptor subtype, 5-HT2A, is a G protein-coupled receptor expressed in multiple regions of the body e.g. gastrointestinal tract, liver, smooth muscles and platelets. It is also expressed in many areas of the central nervous system, which include the cortex and hippocampus1,2,3...
Interestingly, both the serotonin transporter and some serotonin receptor subtypes implicated in OCD are highly expressed in the nucleus accumbens where they could influence functioning of the affective basal ganglia thalamocortical circuit. In theory, dopamine as another neuromodulator of this circuit ...
whereas the 45% homologous 5-HT2B receptor subtype signal through various phospholipases (i.e. PLC-β, PLA)18. This 5-HT2B receptor subtype has been widely studied in human dendritic cells (DCs) where it is reported to promote anti-inflammatory functions. Human monocytes cultured in the pre...
Ward RP, Hamblin MW, Lachowicz JE, Hoffman BJ, Sibley DR, Dorsa DM: Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry. Neuroscience. 1995, 64: 1105-1111. 10.1016/0306-4522(94)00439-C. Article CAS PubMed Google Scholar Hirst...
We demonstrate that tissue injury-induced persistent, but not acute, nociception is significantly reduced after functional elimination of this receptor subtype. Specifically, in the setting of tissue injury, the 5-HT3receptor mediates activation of nociceptors but does not contribute to injury-associated...
the 5-hydroxytryptamine subtype 2 (5-HT2) serotonin antagonistketanserinand the 5-HT3antagonistondansetroneach inhibited secretin-stimulated pancreatic volume andbicarbonatesecretion (263), suggesting that serotonin may mediate the effects ofsecretinthrough both 5-HT2 and 5-HT3receptor subtypes. Interestin...
Role of the serotonin receptor subtype 5-HT1D on basal and stimulated growth hormone secretion 来自 NCBI 喜欢 0 阅读量: 21 作者:A Mota,A Bento,A Peñalva,M Pombo,C Dieguez 展开 摘要: At present, four main types of serotonin (5-HT) receptors have been identified in the brain (5...
d5-HT1B not only affects circadian photosensitivity when over- or underexpressed, it also appears to be the major receptor subtype required for the inhibitory effects of serotonin on entrainment. Notably, when d5-HT1B was knocked down with the RNAi transgene driven by tim-Gal4, the effect ...
Serotonin 1Dα receptor activity The ability of the compounds of this invention to bind to the 5-HT1Dα receptor subtype was measured essentially as described in N. Adham, et al., Proceedings of the National Academy of Sciences (USA), 90, 408-412 (1993). Membrane Preparation: Membranes wer...