‘Call’ derives from computer science, meaning to invoke a particular task; detected SVs are the result of each performed ‘task’. Sensitivity The ability to detect known variants correctly. Low sensitivity implies low ability to detect bona fide variants. Reference data sets High-resolution ...
3B). Around 10.2% (148,142/1,455,046) of replicable DHS are cell-type specific, meaning that they are active in one cell type, and only 1,773 out of 1,455,046 replicable DHS are constitutive, meaning that they are active in all 194 cell types. Median length of replicable DHS is ...
Computer science Ambiguous fragment assignment for high-throughput sequencing experiments UNIVERSITY OF CALIFORNIABERKELEY Lior Pachter RobertsAdamAuthor(s): Roberts, Adam | Advisor(s): Pachter, Lior | Abstract: As the cost of short-read, high-throughput DNA sequencing continues to fall rapidly, new ...
The increasing output of the new sequencing technologies continually raises the requirements for computer resources and bioinformatic competence to handle the data [48]. Furthermore, the rate of generation of sequence data increases much faster than the capacity of storing data, suggesting that storage ...
“We always knew there were parts missing, but I don’t think any of us appreciated how extensive they were, or how interesting,” says Michael Schatz, professor of computer science and biology at Johns Hopkins University and another senior author of the same paper. ...
Such students may understand the surface meaning of individual vocabulary words in a sentence but lack the ability to comprehend the overall meaning of the sentence. Such problems have indirectly influenced the English reading, speaking, and writing ability of learners; however, these conditions can ...
The ongoing argument centers on divergent opinions concerning the meaning and relevance of the findings. The primary criticism has been that the findings are pure coincidence and that similar findings could be found in other books. For example, Australian mathematician Brendan McKay did searches of ...
are extremely subtle and can only be seen using specialized equipment and processes. Otherwise, theelements that make up natural diamondsare essentially the same as those that make up their lab-grown counterparts, meaning both types of these rare crystals have the same physical and chemical ...
Then, the FASTQ files were re-analysed by STRait Razor v2s12 software with the default analytical threshold (AT = 2 reads) and heterozygote threshold (HT = 0.40, the same meaning with intralocus balance threshold). In-house workbooks (written by VBA using Microsoft Excel) were ...
Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, USA Chris J. Frangieh Department of Biology, MIT, Cambridge, MA, USA Aviv Regev Contributions J.Z.L., A.R., G.A. and O.R.R. conceptualized the approaches used. X.A. performed PBMC experimentation and Illumina...