网络蛋白 网络释义 1. 蛋白 ...对DNA具有识别特异性,又称序列特异性DNA结 合蛋白(sequence specific DNA binding proteins) ? ◆具有多种功能,包括基 … www.docin.com|基于 1 个网页
While it has been known for some time that the c-Myc protein binds to random DNA sequences, no sequence-specific binding activity has been detected. At its carboxyl terminus, c-Myc contains a basic-helix-loop-helix (bHLH) motif, which is important for dimerization and specific DNA binding,...
内容简介· ··· The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the...
a受体相互作用特定的DNA结合序列(响应元素)DNA 结合域,激活目标基因。 The acceptor affects the specific DNA union sequence mutually (response element) the DNA union territory, the activation goal gene.[translate]
proteinandstaphylococcalproteinA-Cfusion.The deletionanalysisimplicatesaroleforthecarboxyl-terminalregionofthe proteininDNAbinding. 71996AcademicPressLimited *CorrespondingauthorKeywords:MuCprotein;chemicalfootprinting;momregulation Introduction Regulationofgeneexpressionisanintricately controlledprocessinvolvingtheDNAbinding ...
Sequence-specificDNABindingbyEcoKI,aTypeIA DNARestrictionEnzyme LynnM.Powell,DavidT.F.DrydenandNoreenE.Murray* InstituteofCell&Molecular Biology,Universityof Edinburgh,TheKing's Buildings,May®eldRoad EdinburghEH93JR,UK ThetypeIDNArestrictionandmodi®cationenzymesofprokaryotesare ...
By using a combination of approaches, we show that S. shibatae TFB mediates sequence-specific interactions with DNA flanking the A box. Thus, sequence-specific DNA recognition by TFB and TBP are codeterminants of promoter strength in Archaea....
DeeperBind: Enhancing Prediction of Sequence Specificities of DNA Binding Proteins Transcription factors (TFs) are macromolecules that bind to cis-regulatory specific sub-regions of DNA promoters and initiate transcription. Finding the ex... HR Hassanzadeh,MD Wang - IEEE International Conference on Bioi...
2B). These observations indicated that the same protein, UMSBP, might be responsible for the specific binding of the two different origin-associated sequences. Table I. Distribution of UMS and H14 DNA binding activities in fractionated C. fasciculata cell extracts FractionSpecific activityYielda UMS...
stand-alone software tool that is fully automatic and handles millions of sequences per experiment. Specificities determined by DeepBind are readily visualized as a weighted ensemble of position weight matrices or as a 'mutation map' that indicates how variations affect binding within a specific ...